TcoF overview
| TcoF: | ERCC2 | |
| GeneID: | 2146 | |
| Name: | General transcription and DNA repair factor IIH helicase subunit XPD | |
| Ensembl: | ENSG00000104884 | |
| Species: | Human | |
| Class: | NA | |
| Family: | Others | |
| Disease: | 101 | |
| Go term: | 64 | |
| Pathway: | 31 | |
| Hallmark: | 2 | |
| Super Enhancer: |
chr19:45870706-45884269 |
|
| Enhancer: |
chr19:45924650-45926520 chr19:45254640-45256910 chr19:45449330-45451720 chr19:45562620-45563640 chr19:45575840-45577520 chr19:45641870-45643490 chr19:45883490-45885780 chr19:45885980-45887860 chr19:45893880-45895130 chr19:46026080-46026900 chr19:46026950-46027090 chr19:46027130-46027350 chr19:46028860-46029200 chr19:46029260-46029390 chr19:46116930-46117860 chr19:46171560-46172730 chr19:46183270-46184860 chr19:46184900-46184980 chr19:46281900-46282520 chr19:46282620-46282690 chr19:45645720-45646770 chr19:45971970-45973890 chr19:46021350-46023150 chr19:45989050-45989310 chr19:46110470-46112650 chr19:46117960-46119050 chr19:46119150-46119710 chr19:46270410-46271290 chr19:45657030-45659040 chr19:45872410-45873390 chr19:46277500-46278200 chr19:46511980-46514280 chr19:45491430-45493650 chr19:45731030-45731230 chr19:45768170-45769480 chr19:45814640-45815000 chr19:45901410-45901520 chr19:45921150-45922350 chr19:45922460-45923580 chr19:46172850-46173190 chr19:46294350-46295570 chr19:45451790-45451950 chr19:46027400-46027820 chr19:45989370-45991720 chr19:45808540-45809670 chr19:46032720-46033700 chr19:45729200-45730910 chr19:45847600-45848790 chr19:45797710-45798400 chr19:46119820-46120020 chr19:46085920-46087880 chr19:46079320-46081780 chr19:46312030-46313860 chr19:46293910-46294160 chr19:45951920-45952720 chr19:45287660-45289050 chr19:45303710-45303800 chr19:45312460-45314480 chr19:45324080-45324170 chr19:45375590-45377170 chr19:45385620-45386370 chr19:45394950-45395640 chr19:45395720-45396090 chr19:45396190-45397030 chr19:45409100-45409850 chr19:45409920-45411010 chr19:45417990-45418120 chr19:45418210-45419440 chr19:45422610-45425050 chr19:45430290-45430860 chr19:45525680-45526680 chr19:45527760-45528580 chr19:45528680-45528860 chr19:45529000-45529880 chr19:45542370-45543440 chr19:45563970-45564750 chr19:45568450-45570590 chr19:45584690-45586420 chr19:45590330-45591430 chr19:45643530-45643760 chr19:45643860-45644570 chr19:45645470-45645560 chr19:45766620-45767940 chr19:45768010-45768090 chr19:45781870-45783630 chr19:45888120-45888810 chr19:45888990-45889080 chr19:45899140-45899420 chr19:46120110-46120880 chr19:46130790-46133200 chr19:46303820-46305370 chr19:46345830-46347280 chr19:46347460-46348310 chr19:46498760-46500840 chr19:45338450-45339340 chr19:45342320-45343000 chr19:45558200-45558940 chr19:45720320-45720780 chr19:45735130-45737450 chr19:45811790-45814130 chr19:46487160-46488300 chr19:45810190-45810710 chr19:45851420-45851900 chr19:45851990-45852070 chr19:45852180-45852680 chr19:45852860-45853590 chr19:46040500-46041810 chr19:46136230-46136320 chr19:46200440-46201800 chr19:45314600-45315410 chr19:45315650-45315730 chr19:45315810-45316500 chr19:45850030-45850700 chr19:45850780-45851190 chr19:45872250-45872320 chr19:46278290-46278950 chr19:46405080-46405820 chr19:45252300-45254480 chr19:45382200-45383780 chr19:45603900-45605470 chr19:45994290-45996410 chr19:46133300-46135100 chr19:46135210-46136110 chr19:46224900-46226600 chr19:45477860-45479390 chr19:46223660-46224820 chr19:45714590-45715870 chr19:45733380-45735020 chr19:45844100-45846420 chr19:46084020-46085240 chr19:46255520-46256900 chr19:46269370-46269600 chr19:46379310-46380680 chr19:46454740-46457030 chr19:46465770-46467910 chr19:46481660-46482370 chr19:45056300-45057710 chr19:45101830-45103240 chr19:45105400-45106070 chr19:45106140-45107880 chr19:45125800-45127000 chr19:45128220-45130710 chr19:45130870-45131660 chr19:45138770-45139710 chr19:45150840-45153080 chr19:45156430-45156950 chr19:45162360-45164550 chr19:45164590-45165000 chr19:45175260-45175860 chr19:45179690-45182120 chr19:45185890-45186700 chr19:45215300-45217260 chr19:45220880-45223100 chr19:45235310-45236020 chr19:45237610-45238860 chr19:45239970-45241900 chr19:45241910-45242870 chr19:45266270-45267900 chr19:45270380-45272550 chr19:45281540-45281700 chr19:45282840-45284160 chr19:45284310-45284450 chr19:45284620-45284740 chr19:45298990-45301200 chr19:45301800-45303630 chr19:45353250-45355090 chr19:45362220-45362830 chr19:45431190-45431860 chr19:45511320-45512460 chr19:45543570-45545650 chr19:45572380-45572450 chr19:45572500-45573270 chr19:45948800-45949130 chr19:45974210-45974450 chr19:46023260-46024570 chr19:46024660-46025420 chr19:46025470-46025590 chr19:46025840-46025970 chr19:46038120-46038580 chr19:46076770-46079020 chr19:46114890-46116790 chr19:46265900-46268040 chr19:46327130-46328420 chr19:46403710-46404530 chr19:46522910-46524390 chr19:46524600-46525990 chr19:46559360-46560690 chr19:46568750-46569220 chr19:46571450-46572610 chr19:46572920-46575050 chr19:46683610-46685390 chr19:46685560-46686160 chr19:46695870-46698150 chr19:46713530-46714860 chr19:46714940-46715370 chr19:46715490-46715870 chr19:46724300-46726370 chr19:46801770-46801860 chr19:46857250-46857880 chr19:45055200-45056280 chr19:45153380-45155000 chr19:45267990-45270250 chr19:45512810-45515190 chr19:46873000-46875440 chr19:45721610-45722570 chr19:46095960-46096570 chr19:46351260-46352000 chr19:46349250-46351000 chr19:45800080-45800760 chr19:45900860-45901260 chr19:45974560-45975800 chr19:46489150-46490590 chr19:45561160-45562520 chr19:45698850-45699810 chr19:45747200-45749510 chr19:45766420-45766570 chr19:45802600-45803060 chr19:45810910-45811660 chr19:45918220-45919620 chr19:45620370-45622400 chr19:45622550-45623240 chr19:45624030-45626050 chr19:45626370-45627480 chr19:45627740-45627960 chr19:45797280-45797600 chr19:45781300-45781770 chr19:45508830-45510940 chr19:45659430-45660870 chr19:45978830-45980000 chr19:45987260-45988540 chr19:45694460-45695380 chr19:45619060-45620160 chr19:46381200-46382050 chr19:45819360-45820510 chr19:45923690-45924080 chr19:45924200-45924430 chr19:45713880-45714270 chr19:45950680-45951200 chr19:45955820-45956280 |
|
| Promoter: |
chr19:45853095-45874176 |
ChIP-seq based regulatory details of ERCC2
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_30825 | ERCC2 | cell line | HT-1080 | GSM1092545 | Bone | ChIP-Atlas |
Downstream target genes of ERCC2
Upstream regulatory details of ERCC2
Protein-protein interaction of ERCC2
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| ERCC2 | ERCC3 | Reconstituted Complex | 8152490 | 9606 | 9606 | BIOGRID |
| ERCC2 | GTF2H1 | Reconstituted Complex | 8152490 | 9606 | 9606 | BIOGRID |
| ERCC2 | GTF2H2 | Affinity Capture-Western | 9771713 | 9606 | 9606 | BIOGRID |
| ERCC2 | GTF2H2 | Reconstituted Complex | 9771713 | 9606 | 9606 | BIOGRID |
| ERCC2 | ERCC3 | Reconstituted Complex | 8652557 | 9606 | 9606 | BIOGRID |
| ERCC2 | MNAT1 | Affinity Capture-Western | 10801852 | 9606 | 9606 | BIOGRID |
| ERCC2 | ERCC3 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| ERCC2 | MNAT1 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| ERCC2 | MMS19 | Affinity Capture-Western | 11071939 | 9606 | 9606 | BIOGRID |
| ERCC2 | GTF2H1 | Affinity Capture-Western | 11071939 | 9606 | 9606 | BIOGRID |
| ERCC2 | RAD52 | Affinity Capture-Western | 12372413 | 9606 | 9606 | BIOGRID |
| ERCC2 | MMS19 | Affinity Capture-Western | 22678362 | 9606 | 9606 | BIOGRID |
| ERCC2 | GTF2H2C_2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| ERCC2 | CTPS1 | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| ERCC2 | SPTA1 | Affinity Capture-Western | 16889989 | 9606 | 9606 | BIOGRID |
| ERCC2 | MMS19 | Affinity Capture-Western | 28178521 | 9606 | 9606 | BIOGRID |
| ERCC2 | CIAO1 | Affinity Capture-Western | 28178521 | 9606 | 9606 | BIOGRID |
| ERCC2 | FAM96B | Affinity Capture-Western | 28178521 | 9606 | 9606 | BIOGRID |
| ERCC2 | FAM96B | Affinity Capture-Western | 23585563 | 9606 | 9606 | BIOGRID |
| ERCC2 | CIAO1 | Affinity Capture-Western | 23585563 | 9606 | 9606 | BIOGRID |
| ERCC2 | MMS19 | Affinity Capture-Western | 23585563 | 9606 | 9606 | BIOGRID |
| ERCC2 | MNAT1 | Reconstituted Complex | 32245994 | 9606 | 9606 | BIOGRID |
Annotation of ERCC2
TCGA cancer survival map of ERCC2
Expression of ERCC2
Disease information of ERCC2