TcoF overview
| TcoF: | KDM2B | |
| GeneID: | 10765 | |
| Name: | Lysine-specific demethylase 2B | |
| Ensembl: | ENSG00000089094 | |
| Species: | Human | |
| Class: | NA | |
| Family: | Lysine demethylase | |
| Disease: | 1 | |
| Go term: | 28 | |
| Pathway: | 1 | |
| Hallmark: | 2 | |
| Super Enhancer: |
chr12:122013441-122029141 chr12:121955899-121985687 chr12:122013757-122029226 chr12:122011672-122021631 chr12:122013384-122029069 chr12:122013170-122029156 chr12:121968430-121976611 chr12:122013145-122029390 chr12:122016401-122030810 chr12:121968685-121976451 chr12:122013908-122029345 chr12:122013675-122021635 chr12:122013866-122029134 chr12:122012959-122022085 chr12:121937810-122001359 chr12:122013365-122020858 chr12:121960751-121976885 chr12:121951373-122030709 chr12:122013670-122021723 chr12:122012245-122021531 chr12:122013715-122021424 chr12:122012500-122022463 chr12:122013672-122037430 chr12:122011765-122022435 chr12:122013555-122039524 chr12:122012886-122029411 chr12:122013688-122029073 chr12:122013629-122039443 chr12:122014211-122039527 chr12:122014222-122039725 chr12:122013249-122029302 chr12:122013713-122029454 chr12:122013073-122029158 chr12:122013689-122029294 chr12:122013460-122029553 chr12:121951679-122029935 chr12:121968419-122029186 chr12:121973867-122029293 chr12:122002278-122034938 chr12:122011863-122029426 chr12:121993265-122016329 chr12:121886061-121906172 chr12:122013942-122028978 chr12:121937814-121977150 chr12:121951204-122001275 chr12:121940870-122031001 chr12:122014857-122049195 chr12:122011799-122029416 chr12:122011636-122023087 chr12:121961073-121976193 chr12:121937243-121977694 chr12:122006204-122022464 chr12:121903191-121906826 chr12:122012982-122019444 chr12:122014125-122028992 chr12:122006739-122071662 |
|
| Enhancer: |
chr12:121825380-121827240 chr12:122016850-122017920 chr12:122186350-122188280 chr12:122265980-122267970 chr12:122277740-122277830 chr12:122398660-122399880 chr12:122404980-122405910 chr12:122406080-122408320 chr12:121880830-121881480 chr12:122236600-122237640 chr12:122209460-122211320 chr12:122231150-122231400 chr12:121619080-121620900 chr12:122182750-122184200 chr12:121570900-121573310 chr12:121589490-121591970 chr12:121593950-121594180 chr12:121596400-121598020 chr12:121729030-121729600 chr12:121838020-121840470 chr12:121949390-121951070 chr12:121951210-121953390 chr12:121975970-121978190 chr12:122014140-122016420 chr12:122016470-122016700 chr12:121731990-121734440 chr12:121452400-121454130 chr12:121624690-121625340 chr12:121625740-121627980 chr12:121648100-121650500 chr12:122331520-122332640 chr12:121970860-121972400 chr12:122252840-122254900 chr12:122277960-122278850 chr12:122332750-122333380 chr12:122438550-122439400 chr12:122439500-122441550 chr12:122361900-122364090 chr12:121862160-121863910 chr12:121996690-121997500 chr12:121997800-121999370 chr12:122219980-122221470 chr12:121960510-121962930 chr12:122150870-122152960 chr12:121933130-121934250 chr12:122130560-122131400 chr12:122212630-122212960 chr12:122213040-122213510 chr12:122211420-122212560 chr12:122292700-122294220 chr12:122294530-122295230 chr12:122295340-122295660 chr12:122295730-122296590 chr12:122296610-122296720 chr12:122386970-122389380 chr12:121613280-121614940 chr12:121628150-121629380 chr12:121678670-121680570 chr12:122047720-122050160 chr12:122069720-122071710 chr12:122128840-122129930 chr12:122185920-122186230 chr12:122202790-122205140 chr12:122205180-122206900 chr12:122356620-122357620 chr12:122368180-122369650 chr12:122400070-122401990 chr12:122402060-122404040 chr12:122505190-122507360 chr12:122517170-122518970 chr12:122528530-122530530 chr12:122583830-122584820 chr12:122591350-122593690 chr12:122632720-122633960 chr12:122667840-122668480 chr12:122671920-122672240 chr12:122688350-122689060 chr12:122765740-122767940 chr12:122801400-122803770 chr12:122803900-122805260 chr12:122847660-122848520 chr12:122848660-122849250 chr12:122880210-122881120 chr12:122921570-122922940 chr12:122933360-122935190 chr12:122983410-122985190 chr12:123001980-123003380 chr12:122369790-122372150 chr12:122518980-122521390 chr12:122748750-122750850 chr12:121657940-121659710 chr12:121748100-121749970 chr12:121394170-121395860 chr12:121403280-121404370 chr12:121654510-121654750 chr12:121654800-121654930 chr12:121655080-121657370 chr12:121763610-121764890 chr12:122229050-122231050 chr12:122321120-122321640 chr12:122585150-122585970 chr12:122595560-122597610 chr12:122609430-122611800 chr12:122611910-122612420 chr12:122622140-122622740 chr12:122622840-122622970 chr12:122623100-122623360 chr12:122623530-122624330 chr12:122625050-122625500 chr12:122625630-122626230 chr12:122689230-122690860 chr12:121421560-121423070 chr12:122206980-122208810 chr12:122600910-122603160 chr12:121872190-121873650 chr12:121942070-121942620 chr12:122091170-122092170 chr12:121765040-121766110 chr12:122280820-122281610 chr12:122281740-122282580 chr12:122392900-122394970 chr12:122011710-122012450 chr12:122012490-122013680 chr12:122597780-122598480 chr12:122598710-122599490 chr12:121911730-121913050 chr12:121914060-121914960 chr12:122154420-122155750 chr12:122376790-122377550 chr12:122379600-122380430 chr12:122463520-122465450 chr12:122477800-122480250 chr12:122488330-122490200 chr12:122486120-122487340 chr12:122097260-122099680 chr12:121783840-121784690 chr12:121781060-121783550 chr12:121954040-121954690 chr12:122071970-122073550 chr12:122094600-122097090 chr12:122446570-122447410 chr12:121730040-121730670 chr12:121634030-121636200 chr12:121804430-121805680 |
|
| Promoter: |
chr12:121866899-122018928 |
ChIP-seq based regulatory details of KDM2B
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_31298 | KDM2B | cell line | Leukemia, Myeloid | GSM1612048 | Blood | ChIP-Atlas |
| TcoF_00_31299 | KDM2B | cell line | Leukemia, Myeloid | GSM1612054 | Blood | ChIP-Atlas |
| TcoF_00_31300 | KDM2B | cell line | Leukemia, Myeloid | GSM1612060 | Blood | ChIP-Atlas |
| TcoF_00_31301 | KDM2B | cell line | Leukemia, Myeloid | GSM1612065 | Blood | ChIP-Atlas |
| TcoF_00_31302 | KDM2B | cell line | Leukemia, Myeloid | GSM1612067 | Blood | ChIP-Atlas |
| TcoF_00_31303 | KDM2B | cell line | Leukemia, Myeloid | GSM1612069 | Blood | ChIP-Atlas |
| TcoF_00_31304 | KDM2B | cell line | Leukemia, Myeloid | GSM1612072 | Blood | ChIP-Atlas |
| TcoF_00_30492 | KDM2B | cell line | K-562 | GSM1812033 | Bone Marrow | ChIP-Atlas |
| TcoF_00_30493 | KDM2B | cell line | REH | GSM1812035 | Blood | ChIP-Atlas |
| TcoF_00_30494 | KDM2B | cell line | SUP-B15 | GSM1812037 | Blood | ChIP-Atlas |
| TcoF_00_30495 | KDM2B | cell line | DND-41 | GSM1812039 | Blood | ChIP-Atlas |
| TcoF_00_30496 | KDM2B | cell line | HPB-ALL | GSM1812040 | Blood | ChIP-Atlas |
| TcoF_00_30497 | KDM2B | cell line | K-562 | GSM1812042 | Bone Marrow | ChIP-Atlas |
| TcoF_00_30498 | KDM2B | cell line | ALL-SIL | GSM1812043 | Blood | ChIP-Atlas |
| TcoF_00_30673 | KDM2B | cell line | OCI-LY1 | GSM2171650 | Blood | ChIP-Atlas |
| TcoF_00_30715 | KDM2B | cell line | SEM | GSM2212235 | Blood | ChIP-Atlas |
| TcoF_00_30965 | KDM2B | cell line | hESC H1 | GSM2805867 | Embryo | ChIP-Atlas |
| TcoF_00_30967 | KDM2B | cell line | hESC H1 | GSM2805880 | Embryo | ChIP-Atlas |
| TcoF_00_30968 | KDM2B | cell line | hESC H1 | GSM2805881 | Embryo | ChIP-Atlas |
| TcoF_00_31028 | KDM2B | cell line | HS-SY-II | GSM2916090 | Lung | ChIP-Atlas |
Downstream target genes of KDM2B
Upstream regulatory details of KDM2B
Protein-protein interaction of KDM2B
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| KDM2B | SKP1 | Reconstituted Complex | 16943429 | 9606 | 9606 | BIOGRID |
| KDM2B | BCOR | Affinity Capture-Western | 16943429 | 9606 | 9606 | BIOGRID |
| KDM2B | EZH2 | Affinity Capture-Western | 19202064 | 9606 | 9606 | BIOGRID |
| KDM2B | JUN | Affinity Capture-Western | 17704768 | 9606 | 9606 | BIOGRID |
| KDM2B | CUL1 | Affinity Capture-Western | 17704768 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-Western | 17704768 | 9606 | 9606 | BIOGRID |
| KDM2B | SIN3A | Affinity Capture-Western | 17704768 | 9606 | 9606 | BIOGRID |
| KDM2B | HIST1H3A | Biochemical Activity | 22825849 | 9606 | 9606 | BIOGRID |
| KDM2B | HIST1H3A | Reconstituted Complex | 22825849 | 9606 | 9606 | BIOGRID |
| KDM2B | KDM2B | Biochemical Activity | 22825849 | 9606 | 9606 | BIOGRID |
| KDM2B | UBE2D1 | Biochemical Activity | 22825849 | 9606 | 9606 | BIOGRID |
| KDM2B | RNF2 | Affinity Capture-Western | 23395003 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF1 | Affinity Capture-Western | 23395003 | 9606 | 9606 | BIOGRID |
| KDM2B | RYBP | Affinity Capture-Western | 23395003 | 9606 | 9606 | BIOGRID |
| KDM2B | RNF2 | Affinity Capture-Western | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-Western | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | BCOR | Affinity Capture-Western | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | RNF2 | Affinity Capture-MS | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-MS | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | BCOR | Affinity Capture-MS | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF1 | Affinity Capture-MS | 25533466 | 9606 | 9606 | BIOGRID |
| KDM2B | ACBD3 | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-Western | 17463251 | 9606 | 9606 | BIOGRID |
| KDM2B | CUL1 | Affinity Capture-Western | 26725323 | 9606 | 9606 | BIOGRID |
| KDM2B | RBX1 | Affinity Capture-Western | 26725323 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-Western | 26725323 | 9606 | 9606 | BIOGRID |
| KDM2B | FOS | Affinity Capture-Western | 26725323 | 9606 | 9606 | BIOGRID |
| KDM2B | FOS | Biochemical Activity | 26725323 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-Western | 28614300 | 9606 | 9606 | BIOGRID |
| KDM2B | HIST1H3A | Biochemical Activity | 17994099 | 9606 | 9606 | BIOGRID |
| KDM2B | PRMT5 | Negative Genetic | 26864203 | 9606 | 9606 | BIOGRID |
| KDM2B | RNF2 | Affinity Capture-Western | 29985131 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF1 | Affinity Capture-Western | 29985131 | 9606 | 9606 | BIOGRID |
| KDM2B | H2AFX | Co-localization | 29985131 | 9606 | 9606 | BIOGRID |
| KDM2B | BCOR | Affinity Capture-Western | 29502955 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF1 | Affinity Capture-Western | 29502955 | 9606 | 9606 | BIOGRID |
| KDM2B | SSX1 | Affinity Capture-Western | 29502955 | 9606 | 9606 | BIOGRID |
| KDM2B | BCL6 | Affinity Capture-Western | 29352142 | 9606 | 9606 | BIOGRID |
| KDM2B | SKP1 | Affinity Capture-Western | 30596474 | 9606 | 9606 | BIOGRID |
| KDM2B | KAT5 | Affinity Capture-Western | 31218831 | 9606 | 9606 | BIOGRID |
| KDM2B | KAT5 | Reconstituted Complex | 31218831 | 9606 | 9606 | BIOGRID |
| KDM2B | CREBBP | Affinity Capture-Western | 31531877 | 9606 | 9606 | BIOGRID |
| KDM2B | CREBBP | Reconstituted Complex | 31531877 | 9606 | 9606 | BIOGRID |
| KDM2B | HIST1H3A | Reconstituted Complex | 31531877 | 9606 | 9606 | BIOGRID |
| KDM2B | BCOR | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF1 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF3 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF5 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | BMI1 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | H2AFX | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | RNF2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | YAF2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PCGF6 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PHC1 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | CSNK2A2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PHC3 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | MGA | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | CBX3 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | PHC2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | L3MBTL2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | HIST2H3C | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | CBX6 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| KDM2B | HIST1H3C | Biochemical Activity | 31218831 | 9606 | 9913 | BIOGRID |
Annotation of KDM2B
TCGA cancer survival map of KDM2B
Expression of KDM2B
Disease information of KDM2B