TcoF overview
| TcoF: | MKL1 | |
| GeneID: | 57591 | |
| Name: | megakaryoblastic leukemia (translocation) 1 | |
| Ensembl: | ENSG00000196588 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Others | |
| Disease: | 0 | |
| Go term: | 5 | |
| Pathway: | 2 | |
| Hallmark: | 2 | |
| Super Enhancer: |
chr22:41047398-41077095 chr22:41046742-41079254 chr22:41042211-41079151 chr22:41047022-41079319 chr22:41046770-41079251 chr22:41046837-41079615 chr22:41046402-41081719 chr22:41046422-41118482 chr22:41046976-41081435 chr22:41046848-41080318 chr22:41046612-41080573 chr22:41074492-41129610 chr22:41042251-41080629 chr22:41046781-41080925 chr22:41023907-41051512 chr22:41031710-41051300 chr22:41024773-41051448 chr22:40873621-40935365 chr22:40887420-40935325 chr22:40881712-40932108 chr22:41023675-41051335 chr22:40877975-40916506 chr22:40881626-40932293 chr22:40880854-40909819 chr22:40887800-40932209 chr22:40887673-40943106 chr22:40880959-40910501 chr22:40881352-40932194 chr22:40887401-40932140 chr22:40883180-40910701 chr22:40894578-40909709 chr22:41031558-41051948 chr22:40878366-40910330 chr22:40876836-40939635 chr22:40873350-40940035 chr22:41023076-41051959 chr22:40892001-40931557 chr22:40881156-40909431 chr22:40894446-40909450 chr22:40894656-40909446 chr22:40892128-40909297 chr22:40894509-40909505 chr22:40875165-40939019 chr22:40875234-40909420 chr22:40810782-40906950 chr22:40810656-40860762 chr22:40873380-40940164 chr22:40875400-40965447 chr22:40881252-40932131 chr22:40979319-41055596 chr22:40887619-40914687 chr22:40806554-40838166 chr22:40892473-40931263 chr22:40892473-40931263 chr22:40876061-40964656 chr22:40875352-40964719 chr22:40832108-40909857 chr22:40875282-40940223 chr22:40880666-40939983 chr22:40892662-40932255 chr22:40890052-40910450 chr22:40875616-40910508 chr22:40892111-40909400 chr22:40880864-40965321 chr22:40886555-40939990 chr22:40857485-40939496 chr22:40810693-40836164 chr22:41024483-41063140 chr22:41031513-41051646 chr22:40894793-40909744 chr22:40892134-40910265 chr22:40892183-40910204 chr22:40887405-40932535 chr22:40887463-40940087 chr22:40887410-40932473 chr22:40877876-40935298 chr22:40887093-40940324 chr22:40887458-40940242 chr22:40891633-40910499 chr22:40880763-40940451 chr22:40887329-40932577 chr22:40887469-40932434 chr22:40887324-40932462 chr22:41040543-41051371 chr22:41020134-41076884 chr22:41040322-41050563 chr22:41024166-41079609 chr22:41023572-41079387 chr22:41040107-41051112 |
|
| Enhancer: |
chr22:40817100-40819530 chr22:40704650-40706820 chr22:40819690-40820200 chr22:40813500-40814370 chr22:41403420-41404440 chr22:40591600-40593980 chr22:41030130-41032480 chr22:40742720-40745180 chr22:40892960-40893810 chr22:40650890-40653360 chr22:40653880-40655950 chr22:40980890-40982000 chr22:40982520-40983660 chr22:41027860-41029230 chr22:40894240-40896300 chr22:40671000-40673080 chr22:40610420-40612720 chr22:40613290-40613680 chr22:40731810-40734100 chr22:40887490-40889520 chr22:40900130-40901380 chr22:40989480-40990670 chr22:40450750-40452270 chr22:40574140-40576010 chr22:40904010-40904530 chr22:40907690-40909440 chr22:41443800-41446290 chr22:40668170-40669420 chr22:40978390-40980060 chr22:40677790-40678240 chr22:40935630-40936840 chr22:41176840-41179230 chr22:40792420-40793970 chr22:40794300-40794650 chr22:41543950-41545040 chr22:41621080-41621790 chr22:41687260-41689760 chr22:40937140-40937830 chr22:40990740-40992560 chr22:40993010-40994760 chr22:40997290-40997580 chr22:40992670-40992890 chr22:40380080-40380350 chr22:40380590-40382520 chr22:40391540-40392300 chr22:40441000-40443110 chr22:40617960-40618580 chr22:40846510-40847760 chr22:40876920-40877380 chr22:40878340-40879250 chr22:40903020-40903320 chr22:40962820-40963640 chr22:40984520-40985850 chr22:40615930-40617920 chr22:40845250-40846460 chr22:40659030-40660690 chr22:41064520-41066580 chr22:41122600-41122960 chr22:41123990-41125830 chr22:41347480-41349560 chr22:41920970-41921190 chr22:41921350-41921800 chr22:41926890-41928090 chr22:41928160-41928660 chr22:41960440-41962230 chr22:41204190-41206570 chr22:41925340-41926690 chr22:40585460-40587780 chr22:40644730-40647180 chr22:40836300-40836660 chr22:40867090-40868940 chr22:40956390-40957130 chr22:41144700-41145450 chr22:41397460-41398050 chr22:40582960-40583970 chr22:40795130-40796690 chr22:40796820-40797590 chr22:40797680-40798140 chr22:41122110-41122440 |
|
| Promoter: |
False |
ChIP-seq based regulatory details of MKL1
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_20152 | MKL1 | cell line | A673 | GSM2436680 | Muscle | Cistrome |
| TcoF_00_20143 | MKL1 | cell line | A673 | GSM2436681 | Muscle | Cistrome |
Downstream target genes of MKL1
Upstream regulatory details of MKL1
Protein-protein interaction of MKL1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| MKL1 | SRF | Affinity Capture-Western | 14565952 | 9606 | 9606 | BIOGRID |
| MKL1 | MKL2 | Affinity Capture-Western | 14565952 | 9606 | 9606 | BIOGRID |
| MKL1 | SUPT16H | Affinity Capture-Western | 18036521 | 9606 | 9606 | BIOGRID |
| MKL1 | SSRP1 | Affinity Capture-Western | 18036521 | 9606 | 9606 | BIOGRID |
| MKL1 | KDM3A | Reconstituted Complex | 17991879 | 9606 | 9606 | BIOGRID |
| MKL1 | SRF | Affinity Capture-Western | 17599918 | 9606 | 9606 | BIOGRID |
| MKL1 | SMARCA4 | Affinity Capture-Western | 17599918 | 9606 | 9606 | BIOGRID |
| MKL1 | SMARCA4 | Reconstituted Complex | 17599918 | 9606 | 9606 | BIOGRID |
| MKL1 | SRF | Affinity Capture-Western | 21965288 | 9606 | 9606 | BIOGRID |
| MKL1 | GSK3B | Affinity Capture-Western | 21965288 | 9606 | 9606 | BIOGRID |
| MKL1 | SMAD3 | Affinity Capture-Western | 21965288 | 9606 | 9606 | BIOGRID |
| MKL1 | ACTB | Affinity Capture-Western | 21670154 | 9606 | 9606 | BIOGRID |
| MKL1 | EP300 | Affinity Capture-Western | 26476216 | 9606 | 9606 | BIOGRID |
| MKL1 | FUNDC2 | Proximity Label-MS | 30021884 | 9606 | 9606 | BIOGRID |
Annotation of MKL1
TCGA cancer survival map of MKL1
Expression of MKL1
Disease information of MKL1