TcoF overview
TcoF: NCOA2
GeneID: 8031
Name: Nuclear receptor coactivator 2
Ensembl: ENSG00000140396
Species: Human
Class: NA
Family: Nuclear receptor coactivator
Disease: 6
Go term: 29
Pathway: 27
Hallmark: --
Super Enhancer:

chr8:71240959-71288234 chr8:71313922-71317113 chr8:71313402-71317149 chr8:71313668-71317029 chr8:71310391-71317690 chr8:71313457-71317348 chr8:71305383-71317268 chr8:71242278-71315157 chr8:71305109-71317180 chr8:71299446-71317334 chr8:71297994-71317511 chr8:71299938-71330859 chr8:71313950-71317037 chr8:71313774-71317369 chr8:71313399-71317599 chr8:71278738-71313695 chr8:71226432-71257833 chr8:71198048-71261270 chr8:71313936-71317057 chr8:71059455-71159779 chr8:71216866-71293568 chr8:71040170-71094833 chr8:71038523-71095059 chr8:71305122-71317083 chr8:71313562-71317078 chr8:71313093-71317113 chr8:71313704-71316847 chr8:71313112-71318528 chr8:71313517-71318428 chr8:71084309-71107535 chr8:71198327-71265269 chr8:71313433-71317152 chr8:71313809-71316950 chr8:71312782-71317360

Enhancer:

chr8:70946500-70948840 chr8:71224860-71225980 chr8:71277710-71278680 chr8:71356400-71357160 chr8:71357300-71357990 chr8:70944680-70945750 chr8:70972660-70974270 chr8:71218160-71219460 chr8:71714940-71717030 chr8:71717070-71718370 chr8:70950920-70952060 chr8:71069480-71071730 chr8:71084630-71086990 chr8:71126310-71128570 chr8:71527030-71527830 chr8:71239990-71240610 chr8:71241060-71241810 chr8:71244920-71247300 chr8:71590380-71592520 chr8:71100210-71100800 chr8:71123690-71126130 chr8:71152620-71154330 chr8:71156940-71158130 chr8:71158390-71160090 chr8:71182440-71184250 chr8:71185020-71186880 chr8:71230280-71231300 chr8:71296880-71297280 chr8:71295300-71295550 chr8:71313480-71315940 chr8:71139120-71139620

Promoter:

chr8:71022017-71316043

 ChIP-seq based regulatory details of NCOA2
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_40178 NCOA2 cell line MCF-7 - Breast ReMap
TcoF_00_40179 NCOA2 cell line MCF-7_E2 - Breast ReMap
TcoF_00_40152 NCOA2 cell line K-562 - Bone Marrow ReMap
TcoF_00_40100 NCOA2 cell line K-562 - Bone Marrow ReMap
TcoF_00_30478 NCOA2 cell line hTERT RPE-1 GSM1693903 None ChIP-Atlas
TcoF_00_30480 NCOA2 cell line U2OS GSM1693909 Bone ChIP-Atlas
TcoF_00_30911 NCOA2 cell line THP-1 GSM2661796 Blood ChIP-Atlas
TcoF_00_30912 NCOA2 cell line THP-1 GSM2661798 Blood ChIP-Atlas
TcoF_00_30913 NCOA2 cell line THP-1 GSM2661799 Blood ChIP-Atlas
TcoF_00_30914 NCOA2 cell line THP-1 GSM2661801 Blood ChIP-Atlas
TcoF_00_30915 NCOA2 cell line THP-1 GSM2661802 Blood ChIP-Atlas
TcoF_00_41115 NCOA2 cell line THP-1_Dex GSM2661802 Blood ReMap
TcoF_00_30916 NCOA2 cell line THP-1 GSM2661804 Blood ChIP-Atlas
TcoF_00_30917 NCOA2 cell line THP-1 GSM2661805 Blood ChIP-Atlas
TcoF_00_30918 NCOA2 cell line THP-1 GSM2661807 Blood ChIP-Atlas
TcoF_00_31193 NCOA2 cell Endometrial stromal cells GSM3498601 Uterus ChIP-Atlas
 Downstream target genes of NCOA2
 Protein-protein interaction of NCOA2
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
NCOA2 ESR1 Reconstituted Complex 11937504 9606 9606 BIOGRID
NCOA2 VDR Reconstituted Complex 10748178 9606 9606 BIOGRID
NCOA2 ESRRB Reconstituted Complex 10598588 9606 9606 BIOGRID
NCOA2 NR3C1 Co-crystal Structure 12151000 9606 9606 BIOGRID
NCOA2 CCNT1 Affinity Capture-Western 11704662 9606 9606 BIOGRID
NCOA2 ESR1 Affinity Capture-Western 18499756 9606 9606 BIOGRID
NCOA2 BRCA1 Reconstituted Complex 16860316 9606 9606 BIOGRID
NCOA2 RARA Reconstituted Complex 12503607 9606 9606 BIOGRID
NCOA2 MEF2C Reconstituted Complex 12130539 9606 9606 BIOGRID
NCOA2 CCND3 Reconstituted Complex 12130539 9606 9606 BIOGRID
NCOA2 CDK4 Reconstituted Complex 12130539 9606 9606 BIOGRID
NCOA2 NCOA3 Affinity Capture-Western 18267973 9606 9606 BIOGRID
NCOA2 NCOA1 Affinity Capture-Western 18267973 9606 9606 BIOGRID
NCOA2 ESR1 Two-hybrid 14766010 9606 9606 BIOGRID
NCOA2 CREBBP Affinity Capture-Western 9192892 9606 9606 BIOGRID
NCOA2 ESR1 Affinity Capture-Western 17697320 9606 9606 BIOGRID
NCOA2 USO1 Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 UBR5 Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 CAD Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 WDHD1 Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 CC2D1A Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 TBK1 Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 HSPA2 Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 TBK1 Co-fractionation 16051665 9606 9606 BIOGRID
NCOA2 ATR Affinity Capture-MS 16051665 9606 9606 BIOGRID
NCOA2 MAGEA11 Affinity Capture-Western 20448036 9606 9606 BIOGRID
NCOA2 EP300 Affinity Capture-Western 20448036 9606 9606 BIOGRID
NCOA2 MAGEA11 Affinity Capture-Western 19828458 9606 9606 BIOGRID
NCOA2 MAGEA11 Reconstituted Complex 19828458 9606 9606 BIOGRID
NCOA2 MAGEA11 Two-hybrid 19828458 9606 9606 BIOGRID
NCOA2 NR3C1 Reconstituted Complex 9920895 9606 9606 BIOGRID
NCOA2 THRB Reconstituted Complex 9920895 9606 9606 BIOGRID
NCOA2 PIAS3 Co-crystal Structure 12208521 9606 9606 BIOGRID
NCOA2 HIST4H4 Biochemical Activity 14747462 9606 9606 BIOGRID
NCOA2 HIST3H3 Biochemical Activity 14747462 9606 9606 BIOGRID
NCOA2 ETV1 Biochemical Activity 14747462 9606 9606 BIOGRID
NCOA2 THRB Reconstituted Complex 11435616 9606 9606 BIOGRID
NCOA2 FLII Reconstituted Complex 14966289 9606 9606 BIOGRID
NCOA2 tat Affinity Capture-Western 11704662 9606 11676 BIOGRID
NCOA2 Pias3 Two-hybrid 12208521 9606 10090 BIOGRID
NCOA2 ORF50 Affinity Capture-Western 31751430 9606 37296 BIOGRID
NCOA2 ORF50 Reconstituted Complex 31751430 9606 37296 BIOGRID
 Annotation of NCOA2
 TCGA cancer survival map of NCOA2


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  NCOA2