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TcoF overview
TcoF: NOD2
GeneID: 23636
Name: Nucleotide-binding oligomerization domain-containing protein 2
Ensembl: ENSG00000167207
Species: Human
Class: class HC
Family: Others
Disease: 15
Go term: 76
Pathway: 9
Hallmark: 2
Super Enhancer:

chr16:50774217-50785699 chr16:50774236-50787736 chr16:50710761-50722311 chr16:50725283-50737332 chr16:50698562-50782124 chr16:50698581-50749471 chr16:50701241-50756743 chr16:50698582-50759556 chr16:50698582-50756983 chr16:50698260-50749254 chr16:50698357-50754890 chr16:50712507-50744665 chr16:50712901-50753022 chr16:50698610-50754762 chr16:50698658-50754805 chr16:50698451-50754812 chr16:50698210-50754849 chr16:50697881-50756756
Enhancer:

chr16:50776130-50776670 chr16:50582490-50582620 chr16:50582660-50583330 chr16:50664820-50666190 chr16:50776750-50778640 chr16:50666320-50667100 chr16:50703070-50704510 chr16:50707990-50709680 chr16:50709830-50711080 chr16:50705550-50706880 chr16:50780020-50782380 chr16:50342700-50343450 chr16:50343560-50344360 chr16:50344440-50344590 chr16:50344790-50345600 chr16:50345700-50345940 chr16:50346100-50346800 chr16:50346950-50347860 chr16:50664240-50664730 chr16:50347970-50348200 chr16:50747590-50749250 chr16:50750890-50751870 chr16:50751900-50753830 chr16:50753920-50755030 chr16:50796860-50797610 chr16:50912920-50915200 chr16:50501340-50503650 chr16:50650390-50651630 chr16:50746280-50747380 chr16:50763810-50765650 chr16:50812080-50812800

Promoter:

chr16:50727499-50767952

 ChIP-seq based regulatory details of NOD2
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of NOD2
 Upstream regulatory details of NOD2
 Protein-protein interaction of NOD2
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
NOD2 RIPK2 Affinity Capture-Western 11087742 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 19592251 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 15620648 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 21123652 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 BIRC2 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 BIRC3 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 NAT16 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 XIAP Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 IKBKG Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 RIPK1 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 RNF31 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 RBCK1 Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 SHARPIN Affinity Capture-Western 22607974 9606 9606 BIOGRID
NOD2 GALNT2 Two-hybrid 21699783 9606 9606 BIOGRID
NOD2 FIS1 Two-hybrid 21699783 9606 9606 BIOGRID
NOD2 TLE1 Two-hybrid 21699783 9606 9606 BIOGRID
NOD2 VIM Two-hybrid 21699783 9606 9606 BIOGRID
NOD2 KAT5 Two-hybrid 21699783 9606 9606 BIOGRID
NOD2 PPP2R5E Two-hybrid 21699783 9606 9606 BIOGRID
NOD2 GALNT2 Affinity Capture-Western 21699783 9606 9606 BIOGRID
NOD2 FIS1 Affinity Capture-Western 21699783 9606 9606 BIOGRID
NOD2 TLE1 Affinity Capture-Western 21699783 9606 9606 BIOGRID
NOD2 VIM Affinity Capture-Western 21699783 9606 9606 BIOGRID
NOD2 KAT5 Affinity Capture-Western 21699783 9606 9606 BIOGRID
NOD2 PPP2R5E Affinity Capture-Western 21699783 9606 9606 BIOGRID
NOD2 CASP12 Affinity Capture-Western 18329614 9606 9606 BIOGRID
NOD2 TRIM27 Affinity Capture-Western 22829933 9606 9606 BIOGRID
NOD2 COPS6 Affinity Capture-Western 17337451 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 21097508 9606 9606 BIOGRID
NOD2 TRAF4 Affinity Capture-Western 21097508 9606 9606 BIOGRID
NOD2 MAP3K7 Affinity Capture-Western 17965022 9606 9606 BIOGRID
NOD2 MAP3K7 Affinity Capture-Western 15075345 9606 9606 BIOGRID
NOD2 MAP3K7 Reconstituted Complex 15075345 9606 9606 BIOGRID
NOD2 MAP3K7 Reconstituted Complex 17348859 9606 9606 BIOGRID
NOD2 NOD2 Affinity Capture-Western 23437331 9606 9606 BIOGRID
NOD2 RNF31 Affinity Capture-Western 23818254 9606 9606 BIOGRID
NOD2 RBCK1 Affinity Capture-Western 23818254 9606 9606 BIOGRID
NOD2 SHARPIN Affinity Capture-Western 23818254 9606 9606 BIOGRID
NOD2 ATG16L1 Affinity Capture-Western 19898471 9606 9606 BIOGRID
NOD2 NOD1 Affinity Capture-Western 19898471 9606 9606 BIOGRID
NOD2 UBC Co-crystal Structure 23300079 9606 9606 BIOGRID
NOD2 IRGM Affinity Capture-Western 25891078 9606 9606 BIOGRID
NOD2 IRGM Reconstituted Complex 25891078 9606 9606 BIOGRID
NOD2 CYLD Affinity Capture-Western 26670046 9606 9606 BIOGRID
NOD2 RNF31 Affinity Capture-Western 26670046 9606 9606 BIOGRID
NOD2 RBCK1 Affinity Capture-Western 26670046 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 26670046 9606 9606 BIOGRID
NOD2 SHARPIN Affinity Capture-Western 26670046 9606 9606 BIOGRID
NOD2 TNFAIP3 Affinity Capture-Western 26670046 9606 9606 BIOGRID
NOD2 SPATA2 Affinity Capture-Western 27545878 9606 9606 BIOGRID
NOD2 CYLD Affinity Capture-Western 27545878 9606 9606 BIOGRID
NOD2 RNF31 Affinity Capture-Western 27545878 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 27545878 9606 9606 BIOGRID
NOD2 C10orf67 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 RIPK2 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 DOCK7 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 DCTN1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 GOLGB1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 PRR16 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 ANKHD1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 TRIM41 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 CHMP5 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 SDCCAG3 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 VIM Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 IKBIP Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 GOLGA6L5P Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 KRT15 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 PPP1R12C Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 LDOC1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 PPP2R3B Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 CHMP4B Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 PDLIM5 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 TACC3 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 HAP1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 ANXA2 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 LURAP1L Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 RPL13A Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 ALPI Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 VCP Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 LMNA Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 WBP11 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 TNIP1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 TPM1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 TPM3 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 TPM4 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 SCYL1 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 CCL13 Two-hybrid 27812135 9606 9606 BIOGRID
NOD2 RIPK2 Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 ANKHD1 Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 LDOC1 Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 SDCCAG3 Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 KRT15 Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 TRIM41 Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 VIM Affinity Capture-Western 27812135 9606 9606 BIOGRID
NOD2 CHMP5 FRET 27812135 9606 9606 BIOGRID
NOD2 ANKHD1 FRET 27812135 9606 9606 BIOGRID
NOD2 LDOC1 FRET 27812135 9606 9606 BIOGRID
NOD2 SDCCAG3 FRET 27812135 9606 9606 BIOGRID
NOD2 PPP1R12C FRET 27812135 9606 9606 BIOGRID
NOD2 PPP2R3B FRET 27812135 9606 9606 BIOGRID
NOD2 DOCK7 FRET 27812135 9606 9606 BIOGRID
NOD2 ACSL3 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 BST2 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 CLTA Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 DNAJA1 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 ERBB2IP Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 HADHA Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 MYL9 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 PPP2R1A Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 PPP2R2A Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 RPL34 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 RPL37A Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 SLC25A3 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 SPTLC1 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 SQSTM1 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 SRPRB Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 TCP1 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 TMED1 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 TMED10 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 TMED2 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 TMED9 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 TWF1 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 VDAC2 Affinity Capture-MS 30833792 9606 9606 BIOGRID
NOD2 ATG16L1 Reconstituted Complex 27273576 9606 9606 BIOGRID
NOD2 RBL1 Positive Genetic 30762338 9606 9606 BIOGRID
 Annotation of NOD2
 TCGA cancer survival map of NOD2


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Expression of  NOD2
 Disease information of  NOD2