TcoF overview
TcoF: PLK3
GeneID: 5494
Name: Serine/threonine-protein kinase PLK3
Ensembl: ENSG00000173846
Species: Human
Class: class HC
Family: Others
Disease: 0
Go term: 36
Pathway: 11
Hallmark: 3
Super Enhancer:

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Enhancer:

chr1:45185080-45185530 chr1:45205680-45206580 chr1:45266350-45266510 chr1:45266620-45266700 chr1:45286380-45287930 chr1:45338500-45340200 chr1:45340500-45341280 chr1:45524430-45525770 chr1:45117400-45118910 chr1:45266820-45267290 chr1:45267420-45267510 chr1:45277960-45278660 chr1:45278940-45279040 chr1:45307710-45308530 chr1:45345680-45347280 chr1:45251900-45252130 chr1:45267600-45268430 chr1:45288340-45288740 chr1:45189920-45189990 chr1:45250160-45250300 chr1:45279170-45279300 chr1:45292060-45292150 chr1:45292440-45292570 chr1:45292760-45292830 chr1:45292980-45293070 chr1:45466080-45468210 chr1:45500140-45501350 chr1:45252370-45253040 chr1:45163900-45165140 chr1:45206680-45207030 chr1:45497600-45499980 chr1:45512570-45513060 chr1:45162840-45163730 chr1:45278740-45278800 chr1:45669670-45671420 chr1:45368060-45369640 chr1:45251350-45251740 chr1:45250460-45250570 chr1:45221910-45223220 chr1:45223320-45223570 chr1:45250660-45250770 chr1:45316680-45318730 chr1:45160370-45162770 chr1:45188670-45189790 chr1:45320960-45321880 chr1:45569530-45570910 chr1:45268530-45268620 chr1:45269060-45269150 chr1:45165280-45166590 chr1:45293390-45293510 chr1:45504750-45505550 chr1:45120880-45123320 chr1:44818600-44820560 chr1:44855090-44856650 chr1:44871200-44872780 chr1:44950490-44952510 chr1:45018160-45020420 chr1:45082280-45084060 chr1:45084720-45086400 chr1:45087100-45088360 chr1:45094500-45095310 chr1:45111160-45113260 chr1:45125970-45126560 chr1:45392410-45393490 chr1:45450330-45452160 chr1:44996750-44999040 chr1:44679530-44680020 chr1:44747910-44750250 chr1:45011220-45013650 chr1:45168720-45169170 chr1:45244130-45244240 chr1:45245890-45247740 chr1:45248930-45249170 chr1:45268830-45268930 chr1:45599840-45600830 chr1:45637420-45639000 chr1:45730940-45733350 chr1:45645260-45645970 chr1:45334040-45334920 chr1:45110950-45111080 chr1:45749700-45752080 chr1:45295700-45296510 chr1:45296720-45297370 chr1:44874310-44874990 chr1:45283040-45285520 chr1:45023380-45023770 chr1:45291100-45291920 chr1:44882620-44884420 chr1:45656140-45657430 chr1:45149220-45151290 chr1:45190340-45190430 chr1:45190510-45190800 chr1:45115630-45116370 chr1:45250980-45251270 chr1:45183840-45184690

Promoter:

chr1:45266049-45271662

 ChIP-seq based regulatory details of PLK3
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of PLK3
 Protein-protein interaction of PLK3
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
PLK3 TRIP13 Two-hybrid 16189514 9606 9606 BIOGRID
PLK3 TP53 Biochemical Activity 11551930 9606 9606 BIOGRID
PLK3 CHEK2 Biochemical Activity 12242661 9606 9606 BIOGRID
PLK3 TP53 Biochemical Activity 12242661 9606 9606 BIOGRID
PLK3 TP53 Affinity Capture-Western 12242661 9606 9606 BIOGRID
PLK3 CDC25C Biochemical Activity 10557092 9606 9606 BIOGRID
PLK3 CDC25C Affinity Capture-Western 10557092 9606 9606 BIOGRID
PLK3 CDC25C Reconstituted Complex 10557092 9606 9606 BIOGRID
PLK3 PRNP Affinity Capture-Western 18482256 9606 9606 BIOGRID
PLK3 AURKA Reconstituted Complex 15190214 9606 9606 BIOGRID
PLK3 BUB1B Reconstituted Complex 15190214 9606 9606 BIOGRID
PLK3 BUB1B Affinity Capture-Western 15190214 9606 9606 BIOGRID
PLK3 SNCA Biochemical Activity 19889641 9606 9606 BIOGRID
PLK3 SNCB Biochemical Activity 19889641 9606 9606 BIOGRID
PLK3 CENPU Protein-peptide 19597481 9606 9606 BIOGRID
PLK3 POU2F1 Two-hybrid 25416956 9606 9606 BIOGRID
PLK3 BCL2L1 Biochemical Activity 22617334 9606 9606 BIOGRID
PLK3 HIF1A Reconstituted Complex 20889502 9606 9606 BIOGRID
PLK3 HIF1A Biochemical Activity 20889502 9606 9606 BIOGRID
PLK3 HIF1A Affinity Capture-Western 28515325 9606 9606 BIOGRID
PLK3 PLK1 Two-hybrid 12548019 9606 9606 BIOGRID
PLK3 CHEK2 Two-hybrid 12548019 9606 9606 BIOGRID
PLK3 RRM2 Two-hybrid 12548019 9606 9606 BIOGRID
PLK3 PPM1A Two-hybrid 12548019 9606 9606 BIOGRID
PLK3 TENC1 Two-hybrid 12548019 9606 9606 BIOGRID
PLK3 SLX4 Two-hybrid 12548019 9606 9606 BIOGRID
PLK3 CHEK2 Affinity Capture-Western 12548019 9606 9606 BIOGRID
PLK3 CHEK2 Reconstituted Complex 12548019 9606 9606 BIOGRID
 Annotation of PLK3
 TCGA cancer survival map of PLK3


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  PLK3