TcoF overview
| TcoF: | PRKAA1 | |
| GeneID: | 5700 | |
| Name: | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | |
| Ensembl: | ENSG00000132356 | |
| Species: | Human | |
| Class: | class 2 | |
| Family: | Others | |
| Disease: | 10 | |
| Go term: | 84 | |
| Pathway: | 22 | |
| Hallmark: | 3 | |
| Super Enhancer: |
chr5:40831467-40844374 chr5:40772894-40800581 chr5:40778677-40803727 chr5:40780017-40803027 chr5:40776172-40799619 chr5:40778939-40799508 chr5:40775244-40800018 |
|
| Enhancer: |
chr5:40841770-40843250 chr5:40699740-40701350 chr5:40553670-40555170 chr5:41009510-41010020 chr5:41008900-41009380 chr5:40395220-40395900 chr5:40521070-40522280 chr5:40547520-40549150 chr5:40717410-40717850 chr5:40781780-40782760 chr5:40614640-40616430 chr5:40446620-40448030 chr5:40775610-40777410 chr5:40782890-40785300 chr5:40790760-40793020 chr5:40895290-40896280 chr5:40914850-40915820 chr5:41109210-41109910 chr5:41114800-41116650 chr5:41160470-41161790 chr5:41251460-41252640 chr5:41156330-41157280 chr5:40680580-40681050 chr5:40775070-40775510 chr5:40401220-40402660 chr5:40404400-40405230 chr5:40486160-40487700 chr5:41012840-41013910 |
|
| Promoter: |
chr5:40759481-40798476 |
ChIP-seq based regulatory details of PRKAA1
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of PRKAA1
Upstream regulatory details of PRKAA1
Protein-protein interaction of PRKAA1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| PRKAA1 | MTOR | Protein-peptide | 14970221 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TSC2 | Reconstituted Complex | 14651849 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TSC2 | Reconstituted Complex | 15261145 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TSC2 | Affinity Capture-Western | 14651849 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FNIP1 | Biochemical Activity | 17028174 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CFTR | Reconstituted Complex | 10862786 | 9606 | 9606 | BIOGRID |
| PRKAA1 | EIF5B | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SUPT16H | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FXR2 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PA2G4 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SND1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | G3BP1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PARP1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FMR1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RPL35 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HSP90AA1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HSPA4 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TUBA1A | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CDC37 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SIK3 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | YWHAZ | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | YWHAE | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SIK1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SIK2 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | VCP | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PPP2R1B | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PPP2CA | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | USP2 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | NUAK1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | NUAK2 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | BRSK1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | BRSK2 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MARK1 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MARK2 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MARK3 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MARK4 | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SNRK | Affinity Capture-MS | 16306228 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CFTR | Biochemical Activity | 20861072 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PSMD11 | Biochemical Activity | 19616115 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CRBN | Affinity Capture-Western | 21232561 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Affinity Capture-Western | 21232561 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Affinity Capture-Western | 21232561 | 9606 | 9606 | BIOGRID |
| PRKAA1 | EPM2A | Biochemical Activity | 21728993 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RPTOR | Biochemical Activity | 18439900 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HDAC5 | Biochemical Activity | 22462548 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CRTC2 | Biochemical Activity | 22462548 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ABI1 | Affinity Capture-Western | 20368287 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CPE | Affinity Capture-Western | 20368287 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MDM4 | Biochemical Activity | 24190973 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HSP90AA1 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HSP90AB1 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ACACA | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FKBP5 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG2 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Affinity Capture-MS | 23455922 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ACACA | Biochemical Activity | 18480843 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Two-hybrid | 8621713 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Reconstituted Complex | 8621713 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Reconstituted Complex | 8621713 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Reconstituted Complex | 8663446 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Reconstituted Complex | 8663446 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TRIM27 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | VPS52 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TRIP6 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | BHLHE40 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ZBED1 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ABI2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RBPMS | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | IKZF3 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MTUS2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RAD54B | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ROPN1 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | THAP1 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HOMEZ | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | HMBOX1 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | VPS37B | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TSC22D4 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | L3MBTL3 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RIMBP3 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | UBXN11 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PNMA5 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SSX2IP | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | KRT40 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RFX6 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | INO80E | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TXNIP | Biochemical Activity | 23453806 | 9606 | 9606 | BIOGRID |
| PRKAA1 | EP300 | Affinity Capture-Western | 21567395 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PPM1F | Affinity Capture-Western | 20801214 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FKBP5 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SUN2 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| PRKAA1 | USP10 | Biochemical Activity | 26876938 | 9606 | 9606 | BIOGRID |
| PRKAA1 | USP10 | Reconstituted Complex | 26876938 | 9606 | 9606 | BIOGRID |
| PRKAA1 | USP10 | Affinity Capture-Western | 26876938 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FANCG | Affinity Capture-Western | 27449087 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FANCA | Affinity Capture-Western | 27449087 | 9606 | 9606 | BIOGRID |
| PRKAA1 | FANCA | Biochemical Activity | 27449087 | 9606 | 9606 | BIOGRID |
| PRKAA1 | GLI1 | Affinity Capture-Western | 28562331 | 9606 | 9606 | BIOGRID |
| PRKAA1 | USP10 | Affinity Capture-Western | 30056112 | 9606 | 9606 | BIOGRID |
| PRKAA1 | RPS6KA2 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SPHK2 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CHEK1 | Biochemical Activity | 30428154 | 9606 | 9606 | BIOGRID |
| PRKAA1 | INSIG1 | Affinity Capture-Western | 30733434 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TSC2 | Biochemical Activity | 28059666 | 9606 | 9606 | BIOGRID |
| PRKAA1 | BRD4 | Affinity Capture-Western | 29172540 | 9606 | 9606 | BIOGRID |
| PRKAA1 | GNB2L1 | Biochemical Activity | 24166503 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ULK1 | Affinity Capture-Western | 21460634 | 9606 | 9606 | BIOGRID |
| PRKAA1 | GNB2L1 | Biochemical Activity | 26549445 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG1 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAB1 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PRKAG2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PARS2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ARMCX3 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PDLIM5 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | DCLRE1C | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SDCCAG3 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PLCXD2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | OR5M3 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | AMER1 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | PIEZO2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CHRNB4 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | NTNG2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | TRMT44 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SPRED1 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | ZFP37 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SLC6A3 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CCDC80 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CNR2 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SCNN1D | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | DOCK5 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MRPS21 | Affinity Capture-MS | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | DCLRE1C | Affinity Capture-Western | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | SDCCAG3 | Affinity Capture-Western | 31900314 | 9606 | 9606 | BIOGRID |
| PRKAA1 | AGAP2 | Biochemical Activity | 30833542 | 9606 | 9606 | BIOGRID |
| PRKAA1 | MAP3K7 | Affinity Capture-Western | 31995728 | 9606 | 9606 | BIOGRID |
| PRKAA1 | STK11 | Affinity Capture-Western | 31995728 | 9606 | 9606 | BIOGRID |
| PRKAA1 | AXIN1 | Affinity Capture-Western | 31995728 | 9606 | 9606 | BIOGRID |
| PRKAA1 | CAMKK2 | Affinity Capture-Western | 31995728 | 9606 | 9606 | BIOGRID |
| PRKAA1 | Sde2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Mtfr2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Xrn2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Abi1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Prkag1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Prkag2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Cherp | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Emilin1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Arhgap22 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Lzts2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Maged1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Nab2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Nrbf2 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Prkab1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Rc3h1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Sorbs1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Tfpt | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Thap7 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Trip6 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Wdr62 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Aprt | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Bhlhe40 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Cpe | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Grn | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Hspb1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Kif1c | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Nedd1 | Two-hybrid | 20368287 | 9606 | 10090 | BIOGRID |
| PRKAA1 | Trp53 | Biochemical Activity | 15866171 | 9606 | 10090 | BIOGRID |
| PRKAA1 | CYCS | Biochemical Activity | 27758862 | 9606 | 9913 | BIOGRID |
Annotation of PRKAA1
TCGA cancer survival map of PRKAA1
Expression of PRKAA1
Disease information of PRKAA1