TcoF overview
| TcoF: | RNF8 | |
| GeneID: | 6195 | |
| Name: | E3 ubiquitin-protein ligase RNF8 | |
| Ensembl: | ENSG00000112130 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Ring finger protein | |
| Disease: | 1 | |
| Go term: | 38 | |
| Pathway: | 6 | |
| Hallmark: | 3 | |
| Super Enhancer: |
chr6:37224745-37282774 chr6:37285447-37288934 chr6:37206479-37283695 chr6:37276751-37293040 chr6:37206127-37283328 chr6:37320860-37350567 chr6:37266484-37287733 chr6:37275887-37293323 chr6:37275710-37293895 chr6:37271909-37295035 chr6:37268012-37294074 |
|
| Enhancer: |
chr6:37590020-37591170 chr6:37681100-37682100 chr6:37139270-37140770 chr6:37401150-37403390 chr6:37337000-37339280 chr6:37138430-37138540 chr6:37138660-37138750 chr6:37138800-37138900 chr6:37386500-37386950 chr6:37342760-37344700 chr6:37502120-37502700 chr6:37502730-37503300 chr6:37259130-37260400 chr6:37362520-37363470 chr6:37381470-37381940 chr6:37485720-37486470 chr6:37478790-37479550 chr6:37479910-37481290 chr6:37482060-37483130 chr6:37483310-37485370 chr6:37504060-37505650 chr6:37662730-37664520 chr6:37340300-37340920 chr6:36853800-36855790 chr6:37104320-37106570 chr6:37189090-37191250 chr6:37209090-37211390 chr6:37206380-37208760 chr6:37253630-37254120 chr6:37451070-37452580 chr6:37349130-37351480 chr6:37452630-37452870 chr6:36951270-36953620 chr6:36974360-36975370 chr6:37255450-37256540 chr6:37515050-37516430 chr6:37516780-37517350 chr6:37520690-37523140 chr6:37256630-37259010 chr6:37440260-37441240 chr6:37441380-37442290 chr6:37617040-37617880 chr6:36887480-36888380 chr6:37044630-37046910 chr6:37083040-37084060 chr6:37108570-37110990 chr6:37682240-37683550 chr6:36386070-36388530 chr6:36525350-36526860 chr6:36562260-36564540 chr6:36572240-36573460 chr6:36573520-36574200 chr6:36574300-36574750 chr6:36574990-36576230 chr6:36610360-36612120 chr6:36612180-36612670 chr6:36618630-36619050 chr6:36629440-36631540 chr6:36826020-36828380 chr6:37006050-37007080 chr6:37028660-37030930 chr6:37048730-37049270 chr6:37053670-37053880 chr6:37063040-37064880 chr6:37122660-37124850 chr6:37124960-37125440 chr6:37204170-37205640 chr6:37211420-37213550 chr6:37247390-37248680 chr6:36616130-36618340 chr6:36896740-36898880 chr6:37076970-37079370 chr6:37125520-37127740 chr6:36927140-36929220 chr6:37095520-37097180 chr6:37373750-37375180 chr6:37543350-37545430 chr6:37591530-37591830 chr6:37591910-37593750 chr6:37611720-37612270 chr6:37615290-37616750 chr6:37623670-37626020 chr6:36534280-36535120 chr6:36564750-36566620 chr6:36566760-36567590 chr6:36568050-36568920 chr6:36652320-36653520 chr6:36718440-36720810 chr6:36922710-36924520 chr6:36931390-36931590 chr6:36931740-36932160 chr6:36932610-36933900 chr6:36936750-36937810 chr6:36988400-36988480 chr6:36991070-36991640 chr6:36992450-36993180 chr6:37025460-37026430 chr6:37074800-37075190 chr6:37098000-37100190 chr6:37587620-37589030 chr6:36747970-36750210 chr6:36929410-36929660 chr6:37026700-37028610 chr6:36568970-36569480 chr6:37250730-37252110 chr6:37427460-37429320 chr6:37066200-37068330 chr6:37275340-37277050 chr6:37286290-37287800 chr6:37606440-37607390 chr6:36979630-36981380 chr6:37278800-37280690 chr6:36829570-36831520 chr6:37634800-37635890 chr6:36695470-36696470 chr6:36696580-36698440 chr6:36756540-36757660 chr6:36788050-36789880 chr6:36993720-36994510 chr6:37159410-37160180 chr6:37160230-37162100 chr6:37582720-37584130 chr6:36649530-36651870 chr6:36730770-36733110 chr6:37325580-37327890 chr6:37717130-37719080 chr6:37744510-37745900 chr6:37447030-37447780 chr6:37333380-37333970 chr6:37418910-37419580 chr6:37419650-37420820 chr6:37420920-37421010 chr6:37330790-37331130 chr6:37339350-37339690 chr6:36916180-36917210 chr6:36950480-36950860 |
|
| Promoter: |
chr6:37321755-37362510 |
ChIP-seq based regulatory details of RNF8
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of RNF8
Upstream regulatory details of RNF8
Protein-protein interaction of RNF8
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| RNF8 | CEP44 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| RNF8 | CCDC85B | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| RNF8 | RNF8 | Biochemical Activity | 11322894 | 9606 | 9606 | BIOGRID |
| RNF8 | MDC1 | Reconstituted Complex | 18001825 | 9606 | 9606 | BIOGRID |
| RNF8 | MDC1 | Affinity Capture-Western | 18001824 | 9606 | 9606 | BIOGRID |
| RNF8 | MDC1 | Reconstituted Complex | 18006705 | 9606 | 9606 | BIOGRID |
| RNF8 | HERC2 | Affinity Capture-Western | 20023648 | 9606 | 9606 | BIOGRID |
| RNF8 | HERC2 | Affinity Capture-MS | 20023648 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Affinity Capture-Western | 21911360 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2E2 | Affinity Capture-Western | 21911360 | 9606 | 9606 | BIOGRID |
| RNF8 | CHD4 | Affinity Capture-Western | 22531782 | 9606 | 9606 | BIOGRID |
| RNF8 | HERC2 | Affinity Capture-Western | 22508508 | 9606 | 9606 | BIOGRID |
| RNF8 | KDM4A | Biochemical Activity | 22373579 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Reconstituted Complex | 22589545 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2V2 | Reconstituted Complex | 22589545 | 9606 | 9606 | BIOGRID |
| RNF8 | XRCC5 | Affinity Capture-Western | 22266820 | 9606 | 9606 | BIOGRID |
| RNF8 | RNF8 | Biochemical Activity | 22266820 | 9606 | 9606 | BIOGRID |
| RNF8 | CHEK2 | Affinity Capture-Western | 22266820 | 9606 | 9606 | BIOGRID |
| RNF8 | CHEK2 | Biochemical Activity | 22266820 | 9606 | 9606 | BIOGRID |
| RNF8 | PCNA | Biochemical Activity | 18948756 | 9606 | 9606 | BIOGRID |
| RNF8 | PCNA | Affinity Capture-Western | 18948756 | 9606 | 9606 | BIOGRID |
| RNF8 | YEATS4 | Two-hybrid | 22068108 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Two-hybrid | 18678647 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2E2 | Reconstituted Complex | 11322894 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2E3 | Reconstituted Complex | 11322894 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2D1 | Reconstituted Complex | 11322894 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2E1 | Reconstituted Complex | 11322894 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2D3 | Reconstituted Complex | 22373579 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2D1 | Reconstituted Complex | 22266820 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2D3 | Reconstituted Complex | 18948756 | 9606 | 9606 | BIOGRID |
| RNF8 | NBN | Biochemical Activity | 23115235 | 9606 | 9606 | BIOGRID |
| RNF8 | HIST2H2AC | Biochemical Activity | 22980979 | 9606 | 9606 | BIOGRID |
| RNF8 | H2AFX | Biochemical Activity | 22980979 | 9606 | 9606 | BIOGRID |
| RNF8 | PCNA | Biochemical Activity | 22980979 | 9606 | 9606 | BIOGRID |
| RNF8 | HIST2H2BE | Biochemical Activity | 22980979 | 9606 | 9606 | BIOGRID |
| RNF8 | RPSA | Two-hybrid | 22814251 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Two-hybrid | 22814251 | 9606 | 9606 | BIOGRID |
| RNF8 | HERC2 | Two-hybrid | 22814251 | 9606 | 9606 | BIOGRID |
| RNF8 | RPSA | Affinity Capture-Western | 22814251 | 9606 | 9606 | BIOGRID |
| RNF8 | BLM | Biochemical Activity | 23708797 | 9606 | 9606 | BIOGRID |
| RNF8 | JMJD1C | Reconstituted Complex | 24240613 | 9606 | 9606 | BIOGRID |
| RNF8 | JMJD1C | Affinity Capture-Western | 24240613 | 9606 | 9606 | BIOGRID |
| RNF8 | MDC1 | Affinity Capture-Western | 24240613 | 9606 | 9606 | BIOGRID |
| RNF8 | BCL10 | Affinity Capture-Western | 24732096 | 9606 | 9606 | BIOGRID |
| RNF8 | TNFRSF1A | Affinity Capture-Western | 24980434 | 9606 | 9606 | BIOGRID |
| RNF8 | HERC2 | Affinity Capture-Western | 25305019 | 9606 | 9606 | BIOGRID |
| RNF8 | USP16 | Affinity Capture-Western | 25305019 | 9606 | 9606 | BIOGRID |
| RNF8 | PNMA2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| RNF8 | RBFOX2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| RNF8 | SEPT3 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| RNF8 | HOMEZ | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| RNF8 | TMEM79 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| RNF8 | UBC | Biochemical Activity | 22266820 | 9606 | 9606 | BIOGRID |
| RNF8 | BLM | Reconstituted Complex | 23708797 | 9606 | 9606 | BIOGRID |
| RNF8 | UBC | Biochemical Activity | 25909880 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Reconstituted Complex | 25909880 | 9606 | 9606 | BIOGRID |
| RNF8 | MDC1 | Affinity Capture-Western | 25512560 | 9606 | 9606 | BIOGRID |
| RNF8 | WRAP53 | Affinity Capture-Western | 25512560 | 9606 | 9606 | BIOGRID |
| RNF8 | H2AFX | Biochemical Activity | 26507658 | 9606 | 9606 | BIOGRID |
| RNF8 | UBC | Biochemical Activity | 26285145 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Reconstituted Complex | 26285145 | 9606 | 9606 | BIOGRID |
| RNF8 | NBN | Affinity Capture-Western | 26869104 | 9606 | 9606 | BIOGRID |
| RNF8 | VRK1 | Affinity Capture-Western | 26869104 | 9606 | 9606 | BIOGRID |
| RNF8 | TRIM29 | Reconstituted Complex | 26381412 | 9606 | 9606 | BIOGRID |
| RNF8 | TRIM29 | Affinity Capture-Western | 26381412 | 9606 | 9606 | BIOGRID |
| RNF8 | MAGED1 | Reconstituted Complex | 27035619 | 9606 | 9606 | BIOGRID |
| RNF8 | BARD1 | Affinity Capture-Western | 27035619 | 9606 | 9606 | BIOGRID |
| RNF8 | MAGED1 | Affinity Capture-Western | 27035619 | 9606 | 9606 | BIOGRID |
| RNF8 | POLD4 | Biochemical Activity | 23233665 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2D3 | Reconstituted Complex | 23233665 | 9606 | 9606 | BIOGRID |
| RNF8 | FOXM1 | Affinity Capture-Western | 27526106 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | FRET | 27909234 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Reconstituted Complex | 27909234 | 9606 | 9606 | BIOGRID |
| RNF8 | RNF8 | Biochemical Activity | 28525740 | 9606 | 9606 | BIOGRID |
| RNF8 | HIST2H2AC | Biochemical Activity | 28525740 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2S | Affinity Capture-Western | 28525740 | 9606 | 9606 | BIOGRID |
| RNF8 | SUMO2 | Two-hybrid | 28983621 | 9606 | 9606 | BIOGRID |
| RNF8 | H3F3B | Affinity Capture-Western | 28507061 | 9606 | 9606 | BIOGRID |
| RNF8 | H3F3B | Reconstituted Complex | 28507061 | 9606 | 9606 | BIOGRID |
| RNF8 | H3F3B | Biochemical Activity | 28507061 | 9606 | 9606 | BIOGRID |
| RNF8 | MDC1 | Affinity Capture-Western | 28943310 | 9606 | 9606 | BIOGRID |
| RNF8 | HIST1H2BB | Biochemical Activity | 28552346 | 9606 | 9606 | BIOGRID |
| RNF8 | PIWIL1 | Affinity Capture-Western | 28552346 | 9606 | 9606 | BIOGRID |
| RNF8 | CHUK | Affinity Capture-Western | 28499869 | 9606 | 9606 | BIOGRID |
| RNF8 | IKBKB | Affinity Capture-Western | 28499869 | 9606 | 9606 | BIOGRID |
| RNF8 | TWIST1 | Affinity Capture-Western | 29748601 | 9606 | 9606 | BIOGRID |
| RNF8 | TP53BP1 | Co-localization | 29499138 | 9606 | 9606 | BIOGRID |
| RNF8 | RYBP | Biochemical Activity | 29320735 | 9606 | 9606 | BIOGRID |
| RNF8 | BLM | Biochemical Activity | 29523790 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Reconstituted Complex | 29523790 | 9606 | 9606 | BIOGRID |
| RNF8 | RNF126 | Affinity Capture-Western | 30529286 | 9606 | 9606 | BIOGRID |
| RNF8 | NONO | Proximity Label-MS | 30445466 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2N | Reconstituted Complex | 31048496 | 9606 | 9606 | BIOGRID |
| RNF8 | RNF8 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | ZNF346 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | AMOTL2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | CEP85 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | UBE2D2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | STX11 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | SH3GL3 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | LMO4 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | TNIP1 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | CCDC50 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | ALS2CR11 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | GPRASP2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | PCYT1A | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | ZNF496 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | TMEM79 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | PGRMC2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | CEP44 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | SCN3B | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | CCDC14 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | CLK2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | FAM9B | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | CLK3 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | FSD2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | KIF24 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | KRTAP9-8 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | KRTAP10-8 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | TOMM20L | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | ZBTB10 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | HOMEZ | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | KRTAP10-1 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | KRTAP9-2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | PNMA2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| RNF8 | PRKDC | Proximity Label-MS | 30021884 | 9606 | 9606 | BIOGRID |
| RNF8 | NONO | Biochemical Activity | 30445466 | 9606 | 9606 | BIOGRID |
| RNF8 | CTNNB1 | Affinity Capture-Western | 32549753 | 9606 | 9606 | BIOGRID |
| RNF8 | RL2 | Affinity Capture-Western | 22405594 | 9606 | 10298 | BIOGRID |
| RNF8 | RL2 | Protein-peptide | 22405594 | 9606 | 10298 | BIOGRID |
Annotation of RNF8
TCGA cancer survival map of RNF8
Expression of RNF8
Disease information of RNF8