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TcoF overview
TcoF: SIRT1
GeneID: 22938
Name: NAD-dependent protein deacetylase sirtuin-1
Ensembl: ENSG00000096717
Species: Human
Class: class HC
Family: Sirtuin
Disease: 85
Go term: 149
Pathway: 20
Hallmark: 5
Super Enhancer:

chr10:69549345-69596328 chr10:69570513-69610943 chr10:69549602-69610491 chr10:69550103-69610219 chr10:69547571-69610400 chr10:69547499-69611507
Enhancer:

chr10:69408580-69410990 chr10:69768160-69770490 chr10:69645160-69647170 chr10:70091970-70092540 chr10:69832940-69834900 chr10:69237340-69238240 chr10:69391990-69393380 chr10:69639160-69639420 chr10:69736070-69737820 chr10:69791980-69792300 chr10:69923220-69924280 chr10:69662200-69664380 chr10:69952480-69953570 chr10:70010070-70012330 chr10:70041770-70042170 chr10:70164600-70166510 chr10:70266480-70268200 chr10:69648880-69650580 chr10:69684940-69686400 chr10:69845420-69846930 chr10:69847180-69848320 chr10:69891890-69893880 chr10:69894640-69895210 chr10:69895260-69895960 chr10:69896020-69896350 chr10:69896490-69898690 chr10:69961750-69963800 chr10:69912600-69915020 chr10:69915080-69916890 chr10:69848370-69849180 chr10:69733520-69736010 chr10:69366810-69367790 chr10:69272310-69273440 chr10:69277950-69279140 chr10:69696020-69696450 chr10:69721590-69722570 chr10:69270670-69271570 chr10:69702910-69704960 chr10:69972110-69973740 chr10:69974560-69975080 chr10:70197000-70198100 chr10:69869480-69871490 chr10:69365140-69366610 chr10:69543070-69545360 chr10:69531700-69534020

Promoter:

chr10:69644414-69678147

 ChIP-seq based regulatory details of SIRT1
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_20388 SIRT1 cell line HCT-116 GSM2474864 Colon Cistrome
TcoF_00_20736 SIRT1 cell line K562 GSM2474867 Bone Marrow Cistrome
TcoF_00_20737 SIRT1 cell line K562 GSM2474868 Bone Marrow Cistrome
TcoF_00_20738 SIRT1 cell line K562 GSM2474869 Bone Marrow Cistrome
TcoF_00_20767 SIRT1 cell line K562 GSM2474870 Bone Marrow Cistrome
TcoF_00_20766 SIRT1 cell line K562 GSM2474871 Bone Marrow Cistrome
 Downstream target genes of SIRT1
 Upstream regulatory details of SIRT1
 Protein-protein interaction of SIRT1
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
SIRT1 HES1 Affinity Capture-Western 12535671 9606 9606 BIOGRID
SIRT1 HES1 Reconstituted Complex 12535671 9606 9606 BIOGRID
SIRT1 HEY2 Reconstituted Complex 12535671 9606 9606 BIOGRID
SIRT1 KAT5 Biochemical Activity 20100829 9606 9606 BIOGRID
SIRT1 SUV39H1 Affinity Capture-Western 19218236 9606 9606 BIOGRID
SIRT1 KAT2B Biochemical Activity 19188449 9606 9606 BIOGRID
SIRT1 KAT2B Affinity Capture-Western 19188449 9606 9606 BIOGRID
SIRT1 E2F1 Affinity Capture-Western 19188449 9606 9606 BIOGRID
SIRT1 KAT5 Affinity Capture-Western 19895790 9606 9606 BIOGRID
SIRT1 MEF2C Co-localization 19553684 9606 9606 BIOGRID
SIRT1 MYOD1 Co-localization 19553684 9606 9606 BIOGRID
SIRT1 RELA Affinity Capture-Western 17041012 9606 9606 BIOGRID
SIRT1 CTTN Affinity Capture-Western 18850005 9606 9606 BIOGRID
SIRT1 CTTN Reconstituted Complex 18850005 9606 9606 BIOGRID
SIRT1 CTTN Biochemical Activity 18850005 9606 9606 BIOGRID
SIRT1 AR Affinity Capture-Western 16923962 9606 9606 BIOGRID
SIRT1 AR Reconstituted Complex 16923962 9606 9606 BIOGRID
SIRT1 AR Biochemical Activity 16923962 9606 9606 BIOGRID
SIRT1 NCOR1 Reconstituted Complex 18829436 9606 9606 BIOGRID
SIRT1 NCOR1 Affinity Capture-Western 18829436 9606 9606 BIOGRID
SIRT1 JUN Affinity Capture-Western 18823944 9606 9606 BIOGRID
SIRT1 DOT1L Affinity Capture-Western 19491102 9606 9606 BIOGRID
SIRT1 CLOCK Affinity Capture-Western 18662547 9606 9606 BIOGRID
SIRT1 ARNTL Affinity Capture-Western 18662547 9606 9606 BIOGRID
SIRT1 CLOCK Reconstituted Complex 18662547 9606 9606 BIOGRID
SIRT1 ARNTL Biochemical Activity 18662547 9606 9606 BIOGRID
SIRT1 HDAC4 Affinity Capture-Western 16166628 9606 9606 BIOGRID
SIRT1 EZH2 Affinity Capture-Western 15684044 9606 9606 BIOGRID
SIRT1 SUZ12 Affinity Capture-Western 15684044 9606 9606 BIOGRID
SIRT1 BCL11A Reconstituted Complex 15639232 9606 9606 BIOGRID
SIRT1 BRINP1 Affinity Capture-Western 18235502 9606 9606 BIOGRID
SIRT1 BRINP1 Reconstituted Complex 18235502 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 18235502 9606 9606 BIOGRID
SIRT1 SIRT2 Affinity Capture-Western 18193082 9606 9606 BIOGRID
SIRT1 RBP1 Affinity Capture-Western 18193082 9606 9606 BIOGRID
SIRT1 ARID4B Affinity Capture-Western 18193082 9606 9606 BIOGRID
SIRT1 ING2 Affinity Capture-Western 18193082 9606 9606 BIOGRID
SIRT1 ING1 Affinity Capture-Western 18193082 9606 9606 BIOGRID
SIRT1 FOXO3 Affinity Capture-Western 15126506 9606 9606 BIOGRID
SIRT1 BHLHE41 Reconstituted Complex 17487425 9606 9606 BIOGRID
SIRT1 TLE1 Two-hybrid 17680780 9606 9606 BIOGRID
SIRT1 TLE1 Affinity Capture-Western 17680780 9606 9606 BIOGRID
SIRT1 ESRRA Biochemical Activity 20484414 9606 9606 BIOGRID
SIRT1 NBN Affinity Capture-Western 17612497 9606 9606 BIOGRID
SIRT1 NBN Reconstituted Complex 17612497 9606 9606 BIOGRID
SIRT1 NBN Biochemical Activity 17612497 9606 9606 BIOGRID
SIRT1 DVL1 Affinity Capture-Western 20439735 9606 9606 BIOGRID
SIRT1 DVL2 Affinity Capture-Western 20439735 9606 9606 BIOGRID
SIRT1 CSNK2A1 Affinity Capture-Western 20439735 9606 9606 BIOGRID
SIRT1 NR0B2 Affinity Capture-Western 20375098 9606 9606 BIOGRID
SIRT1 SETD7 Affinity Capture-Western 21245319 9606 9606 BIOGRID
SIRT1 SETD7 Reconstituted Complex 21245319 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 21245319 9606 9606 BIOGRID
SIRT1 SMAD7 Affinity Capture-Western 17098745 9606 9606 BIOGRID
SIRT1 SMAD7 Reconstituted Complex 17098745 9606 9606 BIOGRID
SIRT1 NR1H4 Reconstituted Complex 19883617 9606 9606 BIOGRID
SIRT1 NR1H4 Biochemical Activity 19883617 9606 9606 BIOGRID
SIRT1 FOXO3 Affinity Capture-Western 20733005 9606 9606 BIOGRID
SIRT1 SREBF1 Biochemical Activity 20595232 9606 9606 BIOGRID
SIRT1 HNF1A Reconstituted Complex 21176092 9606 9606 BIOGRID
SIRT1 HNF1A Affinity Capture-Western 21176092 9606 9606 BIOGRID
SIRT1 BRINP1 Affinity Capture-Western 21030595 9606 9606 BIOGRID
SIRT1 GAPDH Affinity Capture-Western 20972425 9606 9606 BIOGRID
SIRT1 GAPDH Reconstituted Complex 20972425 9606 9606 BIOGRID
SIRT1 ACACA Affinity Capture-Western 19343720 9606 9606 BIOGRID
SIRT1 HSPA4 Affinity Capture-Western 19343720 9606 9606 BIOGRID
SIRT1 WRN Affinity Capture-Western 19343720 9606 9606 BIOGRID
SIRT1 ACACA Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HSPD1 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 CHCHD2 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 DIAPH3 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 YBX1 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 DYNC1H1 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HSPA1L Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HSPA5 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HIST1H2BC Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HIST2H2AB Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HSPA9 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 HDAC2 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 CMYA5 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 KPNA2 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 KPNA3 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 LAMA3 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 EEF1G Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 ARHGAP29 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 MCF2L2 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 ELL3 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 USP9Y Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 NAT10 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 UGDH Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 CACNA1C Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 WRN Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 LANCL1 Affinity Capture-MS 19343720 9606 9606 BIOGRID
SIRT1 ZEB1 Affinity Capture-Western 22249256 9606 9606 BIOGRID
SIRT1 MECOM Affinity Capture-Western 21555002 9606 9606 BIOGRID
SIRT1 KAT8 Affinity Capture-Western 21502975 9606 9606 BIOGRID
SIRT1 KAT8 Reconstituted Complex 21502975 9606 9606 BIOGRID
SIRT1 KAT8 Biochemical Activity 21502975 9606 9606 BIOGRID
SIRT1 CSNK2B Affinity Capture-Western 21968188 9606 9606 BIOGRID
SIRT1 DNMT1 Biochemical Activity 21947282 9606 9606 BIOGRID
SIRT1 DNMT1 Affinity Capture-Western 21947282 9606 9606 BIOGRID
SIRT1 ESR1 Affinity Capture-Western 21920899 9606 9606 BIOGRID
SIRT1 STAT3 Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 JAK1 Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 HSP90AA1 Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 TRIM28 Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 USP22 Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 KAT2A Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 HNRNPK Affinity Capture-Western 22542455 9606 9606 BIOGRID
SIRT1 SATB1 Affinity Capture-Western 22328728 9606 9606 BIOGRID
SIRT1 SATB1 Co-localization 22328728 9606 9606 BIOGRID
SIRT1 FOXO3 Affinity Capture-Western 21713995 9606 9606 BIOGRID
SIRT1 MYCN Affinity Capture-Western 21698133 9606 9606 BIOGRID
SIRT1 HIC1 Affinity Capture-Western 22510409 9606 9606 BIOGRID
SIRT1 TP53 Biochemical Activity 12006491 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 12006491 9606 9606 BIOGRID
SIRT1 JUN Reconstituted Complex 20042607 9606 9606 BIOGRID
SIRT1 FOS Reconstituted Complex 20042607 9606 9606 BIOGRID
SIRT1 JUN Biochemical Activity 20042607 9606 9606 BIOGRID
SIRT1 FOS Biochemical Activity 20042607 9606 9606 BIOGRID
SIRT1 GTF2A1 Co-fractionation 22939629 9606 9606 BIOGRID
SIRT1 SMARCD2 Co-fractionation 22939629 9606 9606 BIOGRID
SIRT1 AKT1 Affinity Capture-Western 21775285 9606 9606 BIOGRID
SIRT1 AKT1 Biochemical Activity 21775285 9606 9606 BIOGRID
SIRT1 USP22 Affinity Capture-Western 23382074 9606 9606 BIOGRID
SIRT1 USP22 Co-fractionation 23382074 9606 9606 BIOGRID
SIRT1 KAT2A Affinity Capture-Western 23382074 9606 9606 BIOGRID
SIRT1 SUPT7L Affinity Capture-Western 23382074 9606 9606 BIOGRID
SIRT1 ATXN7L3 Affinity Capture-Western 23382074 9606 9606 BIOGRID
SIRT1 JUN Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 CREB1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 RPS19BP1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 PUS7 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 SPDL1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 USP22 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 BRINP1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 TULP3 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 PIP5K1A Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 PHLDB3 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 AKIRIN2 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 IQCB1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 JUND Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 ZNHIT6 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 KRT79 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 WDR70 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 NOP14 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 PICALM Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 SERPINB4 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 ARRB2 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 TSPYL1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 RECQL4 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 SCNM1 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 ZNF346 Affinity Capture-MS 23382074 9606 9606 BIOGRID
SIRT1 BRINP1 Affinity Capture-MS 18235501 9606 9606 BIOGRID
SIRT1 NOC4L Affinity Capture-MS 18235501 9606 9606 BIOGRID
SIRT1 SART1 Affinity Capture-MS 18235501 9606 9606 BIOGRID
SIRT1 TAF2 Affinity Capture-MS 18235501 9606 9606 BIOGRID
SIRT1 RAP1A Affinity Capture-MS 18235501 9606 9606 BIOGRID
SIRT1 CHD3 Affinity Capture-MS 18235501 9606 9606 BIOGRID
SIRT1 BRINP1 Affinity Capture-Western 18235501 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 18235501 9606 9606 BIOGRID
SIRT1 TP53 Biochemical Activity 18235501 9606 9606 BIOGRID
SIRT1 RPTOR Affinity Capture-Western 21471201 9606 9606 BIOGRID
SIRT1 MTOR Affinity Capture-Western 21471201 9606 9606 BIOGRID
SIRT1 FOXO3 Affinity Capture-Western 14976264 9606 9606 BIOGRID
SIRT1 FOXO3 Biochemical Activity 14976264 9606 9606 BIOGRID
SIRT1 DNMT1 Affinity Capture-Western 22094255 9606 9606 BIOGRID
SIRT1 EZH2 Affinity Capture-Western 22094255 9606 9606 BIOGRID
SIRT1 SUZ12 Affinity Capture-Western 22094255 9606 9606 BIOGRID
SIRT1 EED Affinity Capture-Western 22094255 9606 9606 BIOGRID
SIRT1 HDAC4 Affinity Capture-Western 23417673 9606 9606 BIOGRID
SIRT1 CAP1 Co-fractionation 22863883 9606 9606 BIOGRID
SIRT1 FASN Co-fractionation 22863883 9606 9606 BIOGRID
SIRT1 KIAA1598 Co-fractionation 22863883 9606 9606 BIOGRID
SIRT1 TPM4 Co-fractionation 22863883 9606 9606 BIOGRID
SIRT1 PPARA Reconstituted Complex 19356714 9606 9606 BIOGRID
SIRT1 KCNA5 Affinity Capture-Western 23390957 9606 9606 BIOGRID
SIRT1 KCNA4 Affinity Capture-Western 23390957 9606 9606 BIOGRID
SIRT1 KCNAB2 Affinity Capture-Western 23390957 9606 9606 BIOGRID
SIRT1 PSME3 Affinity Capture-Western 23612972 9606 9606 BIOGRID
SIRT1 PSME3 Biochemical Activity 23612972 9606 9606 BIOGRID
SIRT1 WRN Biochemical Activity 18203716 9606 9606 BIOGRID
SIRT1 WRN Affinity Capture-Western 18203716 9606 9606 BIOGRID
SIRT1 FOXO1 Affinity Capture-Western 15692560 9606 9606 BIOGRID
SIRT1 PPARGC1A Affinity Capture-Western 15716268 9606 9606 BIOGRID
SIRT1 PPARGC1A Biochemical Activity 15716268 9606 9606 BIOGRID
SIRT1 STK11 Biochemical Activity 18687677 9606 9606 BIOGRID
SIRT1 RPS19BP1 Two-hybrid 17964266 9606 9606 BIOGRID
SIRT1 RPS19BP1 Reconstituted Complex 17964266 9606 9606 BIOGRID
SIRT1 RPS19BP1 Affinity Capture-Western 17964266 9606 9606 BIOGRID
SIRT1 TP53 Biochemical Activity 17964266 9606 9606 BIOGRID
SIRT1 TP53 Reconstituted Complex 17964266 9606 9606 BIOGRID
SIRT1 CDK1 Affinity Capture-Western 19107194 9606 9606 BIOGRID
SIRT1 CCNB1 Affinity Capture-Western 19107194 9606 9606 BIOGRID
SIRT1 IRS2 Biochemical Activity 17901049 9606 9606 BIOGRID
SIRT1 UBE2I Biochemical Activity 23395904 9606 9606 BIOGRID
SIRT1 PARP1 Biochemical Activity 19470756 9606 9606 BIOGRID
SIRT1 PARP1 Affinity Capture-Western 19470756 9606 9606 BIOGRID
SIRT1 PARP1 Reconstituted Complex 19470756 9606 9606 BIOGRID
SIRT1 HIST1H3A Biochemical Activity 19270680 9606 9606 BIOGRID
SIRT1 RICTOR Biochemical Activity 22084251 9606 9606 BIOGRID
SIRT1 EPAS1 Biochemical Activity 22807441 9606 9606 BIOGRID
SIRT1 EPAS1 Affinity Capture-Western 22807441 9606 9606 BIOGRID
SIRT1 CSNK2A2 Affinity Capture-Western 19680552 9606 9606 BIOGRID
SIRT1 CSNK2A1 Affinity Capture-Western 19680552 9606 9606 BIOGRID
SIRT1 NMNAT1 Affinity Capture-Western 19478080 9606 9606 BIOGRID
SIRT1 APEX1 Biochemical Activity 19934257 9606 9606 BIOGRID
SIRT1 APEX1 Affinity Capture-Western 19934257 9606 9606 BIOGRID
SIRT1 SNW1 Two-hybrid 19934264 9606 9606 BIOGRID
SIRT1 SNW1 Reconstituted Complex 19934264 9606 9606 BIOGRID
SIRT1 RARA Reconstituted Complex 19934264 9606 9606 BIOGRID
SIRT1 TSC2 Affinity Capture-Western 20169165 9606 9606 BIOGRID
SIRT1 NOS3 Affinity Capture-Western 20479254 9606 9606 BIOGRID
SIRT1 SIRT1 Biochemical Activity 20479254 9606 9606 BIOGRID
SIRT1 E2F1 Affinity Capture-Western 16892051 9606 9606 BIOGRID
SIRT1 RB1 Affinity Capture-Western 16892051 9606 9606 BIOGRID
SIRT1 E2F1 Reconstituted Complex 16892051 9606 9606 BIOGRID
SIRT1 SREBF1 Biochemical Activity 20817729 9606 9606 BIOGRID
SIRT1 SREBF1 Reconstituted Complex 20817729 9606 9606 BIOGRID
SIRT1 SREBF1 Affinity Capture-Western 20817729 9606 9606 BIOGRID
SIRT1 TP73 Affinity Capture-Western 16998810 9606 9606 BIOGRID
SIRT1 TP73 Biochemical Activity 16998810 9606 9606 BIOGRID
SIRT1 PIK3R1 Affinity Capture-Western 21241768 9606 9606 BIOGRID
SIRT1 IRS1 Affinity Capture-Western 21241768 9606 9606 BIOGRID
SIRT1 IRS2 Affinity Capture-Western 21241768 9606 9606 BIOGRID
SIRT1 SATB1 Biochemical Activity 22328728 9606 9606 BIOGRID
SIRT1 CCAR2 Affinity Capture-Western 25361978 9606 9606 BIOGRID
SIRT1 CHEK2 Affinity Capture-Western 25361978 9606 9606 BIOGRID
SIRT1 EZH2 Affinity Capture-Western 25800736 9606 9606 BIOGRID
SIRT1 EZH2 Biochemical Activity 25800736 9606 9606 BIOGRID
SIRT1 TRIM28 Affinity Capture-Western 25905708 9606 9606 BIOGRID
SIRT1 TRIM28 Biochemical Activity 25905708 9606 9606 BIOGRID
SIRT1 MPHOSPH8 Affinity Capture-Western 25870236 9606 9606 BIOGRID
SIRT1 MPHOSPH8 Biochemical Activity 25870236 9606 9606 BIOGRID
SIRT1 MYC Reconstituted Complex 22190494 9606 9606 BIOGRID
SIRT1 MYC Affinity Capture-Western 22190494 9606 9606 BIOGRID
SIRT1 CCAR2 Affinity Capture-Western 22190494 9606 9606 BIOGRID
SIRT1 ZYX Two-hybrid 19173742 9606 9606 BIOGRID
SIRT1 ZYX Biochemical Activity 19173742 9606 9606 BIOGRID
SIRT1 ZYX Affinity Capture-Western 19173742 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 22689577 9606 9606 BIOGRID
SIRT1 CHFR Affinity Capture-Western 27883020 9606 9606 BIOGRID
SIRT1 CHFR Reconstituted Complex 27883020 9606 9606 BIOGRID
SIRT1 USP22 Affinity Capture-Western 27183383 9606 9606 BIOGRID
SIRT1 HERC2 Affinity Capture-Western 27259994 9606 9606 BIOGRID
SIRT1 USP22 Affinity Capture-Western 28166203 9606 9606 BIOGRID
SIRT1 MDM2 Biochemical Activity 28196907 9606 9606 BIOGRID
SIRT1 MDM2 Affinity Capture-Western 28196907 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 18753379 9606 9606 BIOGRID
SIRT1 TP53 Biochemical Activity 18753379 9606 9606 BIOGRID
SIRT1 NDN Reconstituted Complex 18753379 9606 9606 BIOGRID
SIRT1 MTOR Affinity Capture-Western 26453307 9606 9606 BIOGRID
SIRT1 RICTOR Affinity Capture-Western 26453307 9606 9606 BIOGRID
SIRT1 HOXB9 Reconstituted Complex 27613418 9606 9606 BIOGRID
SIRT1 CCAR2 Affinity Capture-Western 22735644 9606 9606 BIOGRID
SIRT1 TP53 Affinity Capture-Western 22735644 9606 9606 BIOGRID
SIRT1 HIF1A Affinity Capture-Western 20620956 9606 9606 BIOGRID
SIRT1 HIF1A Reconstituted Complex 20620956 9606 9606 BIOGRID
SIRT1 PRMT1 Biochemical Activity 28883095 9606 9606 BIOGRID
SIRT1 HIF1A Affinity Capture-Western 22479397 9606 9606 BIOGRID
SIRT1 UBE2N Affinity Capture-Western 30016968 9606 9606 BIOGRID
SIRT1 HIPK2 Reconstituted Complex 26113041 9606 9606 BIOGRID
SIRT1 RPS19BP1 Affinity Capture-Western 26113041 9606 9606 BIOGRID
SIRT1 BRINP1 Affinity Capture-Western 26113041 9606 9606 BIOGRID
SIRT1 FOXM1 Affinity Capture-Western 27542221 9606 9606 BIOGRID
SIRT1 PPARG Affinity Capture-Western 20660480 9606 9606 BIOGRID
SIRT1 PPARG Co-localization 20660480 9606 9606 BIOGRID
SIRT1 EP300 Co-localization 20660480 9606 9606 BIOGRID
SIRT1 PPARG Biochemical Activity 20660480 9606 9606 BIOGRID
SIRT1 BCL6 Affinity Capture-Western 28754906 9606 9606 BIOGRID
SIRT1 BCL6 Co-localization 28754906 9606 9606 BIOGRID
SIRT1 BRIP1 Biochemical Activity 22792074 9606 9606 BIOGRID
SIRT1 ATG7 Affinity Capture-Western 31072129 9606 9606 BIOGRID
SIRT1 MAPT Biochemical Activity 20869593 9606 9606 BIOGRID
SIRT1 XRCC1 Affinity Capture-Western 31043584 9606 9606 BIOGRID
SIRT1 MAP1LC3A Affinity Capture-Western 25601754 9606 9606 BIOGRID
SIRT1 RFWD2 Affinity Capture-Western 31125554 9606 9606 BIOGRID
SIRT1 TRIB3 Affinity Capture-Western 31125554 9606 9606 BIOGRID
SIRT1 SUMO2 Biochemical Activity 30201799 9606 9606 BIOGRID
SIRT1 TOPBP1 Affinity Capture-MS 31502386 9606 9606 BIOGRID
SIRT1 USP7 Affinity Capture-MS 31502386 9606 9606 BIOGRID
SIRT1 ECT2 Affinity Capture-MS 31502386 9606 9606 BIOGRID
SIRT1 USP22 Affinity Capture-MS 31502386 9606 9606 BIOGRID
SIRT1 HDAC1 Affinity Capture-MS 31502386 9606 9606 BIOGRID
SIRT1 USP7 Affinity Capture-Western 31502386 9606 9606 BIOGRID
SIRT1 CCDC84 Reconstituted Complex 31722219 9606 9606 BIOGRID
SIRT1 CCDC84 Affinity Capture-Western 31722219 9606 9606 BIOGRID
SIRT1 AFP Affinity Capture-Western 31811908 9606 9606 BIOGRID
SIRT1 WDR76 Affinity Capture-MS 31353912 9606 9606 BIOGRID
SIRT1 SMURF2 Affinity Capture-Western 32361710 9606 9606 BIOGRID
SIRT1 SMURF2 Co-localization 32361710 9606 9606 BIOGRID
SIRT1 tat Biochemical Activity 15719057 9606 11676 BIOGRID
SIRT1 tat Affinity Capture-Western 15719057 9606 11676 BIOGRID
SIRT1 Crebbp Affinity Capture-Western 22807441 9606 10090 BIOGRID
SIRT1 Pck1 Biochemical Activity 30193097 9606 10116 BIOGRID
 Annotation of SIRT1
 TCGA cancer survival map of SIRT1


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Expression of  SIRT1
 Disease information of  SIRT1