TcoF overview
TcoF: TOPORS
GeneID: 7158
Name: E3 ubiquitin-protein ligase Topors
Ensembl: ENSG00000197579
Species: Human
Class: NA
Family: Others
Disease: 3
Go term: 38
Pathway: --
Hallmark: 2
Super Enhancer:

chr9:32549867-32574081 chr9:32549817-32559581 chr9:32549857-32574001

Enhancer:

chr9:32384730-32386360 chr9:32626920-32628300 chr9:32571050-32572880 chr9:32421030-32423310 chr9:32424660-32425830 chr9:32426000-32427290 chr9:32430570-32431710 chr9:32431840-32433720 chr9:32488200-32488730 chr9:32644160-32645900 chr9:32423420-32424540 chr9:32558240-32558900 chr9:32558950-32561320 chr9:32523600-32526050 chr9:32716400-32716800 chr9:32393290-32395300 chr9:32427440-32429110 chr9:32395360-32397250 chr9:32500940-32501360 chr9:32502040-32503790 chr9:32485660-32487460 chr9:32487630-32487940 chr9:32434700-32435430 chr9:33025380-33026470 chr9:32166000-32166740 chr9:32664930-32666100 chr9:32671830-32673560 chr9:32738010-32739640 chr9:32603260-32605670 chr9:32344440-32344820 chr9:32508290-32509520 chr9:32516260-32517390 chr9:32570120-32570480

Promoter:

chr9:32540542-32552584

 ChIP-seq based regulatory details of TOPORS
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of TOPORS
 Protein-protein interaction of TOPORS
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
TOPORS UBE2I Two-hybrid 14516784 9606 9606 BIOGRID
TOPORS SUMO1 Two-hybrid 14516784 9606 9606 BIOGRID
TOPORS TOP1 Affinity Capture-Western 10352183 9606 9606 BIOGRID
TOPORS TOP1 Two-hybrid 10352183 9606 9606 BIOGRID
TOPORS TP53 Two-hybrid 11842245 9606 9606 BIOGRID
TOPORS UBE2D1 Reconstituted Complex 19053840 9606 9606 BIOGRID
TOPORS UBE2D1 Affinity Capture-Western 19053840 9606 9606 BIOGRID
TOPORS TP53 Biochemical Activity 15247280 9606 9606 BIOGRID
TOPORS TP53 Reconstituted Complex 17803295 9606 9606 BIOGRID
TOPORS GTF2I Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS NONO Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS SFPQ Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS SIN3A Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS PARP1 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS SAFB2 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS DDB2 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS RBBP7 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS TRIM28 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS RBBP4 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS SMARCC2 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS DHX15 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS HNRNPL Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS RANGAP1 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS UPF3A Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS HNRNPM Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS HNRNPA1 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS SF3B1 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS EEF1A1 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS S100A9 Affinity Capture-MS 17803295 9606 9606 BIOGRID
TOPORS SIN3A Biochemical Activity 17803295 9606 9606 BIOGRID
TOPORS NKX3-1 Reconstituted Complex 18077445 9606 9606 BIOGRID
TOPORS NKX3-1 Biochemical Activity 18077445 9606 9606 BIOGRID
TOPORS TOP1 Biochemical Activity 20805487 9606 9606 BIOGRID
TOPORS TOP1 Biochemical Activity 17976381 9606 9606 BIOGRID
TOPORS IKBKE Co-localization 20188669 9606 9606 BIOGRID
TOPORS PML Co-localization 20188669 9606 9606 BIOGRID
TOPORS TP53 Affinity Capture-Western 17290218 9606 9606 BIOGRID
TOPORS H2AFX Affinity Capture-Western 22972498 9606 9606 BIOGRID
TOPORS PLK1 Affinity Capture-Western 22972498 9606 9606 BIOGRID
TOPORS H2AFX Biochemical Activity 22972498 9606 9606 BIOGRID
TOPORS UBE2D1 Reconstituted Complex 18077445 9606 9606 BIOGRID
TOPORS UBE2D1 Reconstituted Complex 15247280 9606 9606 BIOGRID
TOPORS UBE2D3 Reconstituted Complex 15247280 9606 9606 BIOGRID
TOPORS UBE2E1 Reconstituted Complex 15247280 9606 9606 BIOGRID
TOPORS PLK1 Affinity Capture-Western 19473992 9606 9606 BIOGRID
TOPORS UBC Biochemical Activity 15247280 9606 9606 BIOGRID
TOPORS TP53 Biochemical Activity 16122737 9606 9606 BIOGRID
TOPORS UBE2I Reconstituted Complex 16122737 9606 9606 BIOGRID
TOPORS PSMC1 Two-hybrid 26872363 9606 9606 BIOGRID
TOPORS PSMC1 Affinity Capture-Western 26872363 9606 9606 BIOGRID
TOPORS XRCC1 Far Western 29668892 9606 9606 BIOGRID
 Annotation of TOPORS
 TCGA cancer survival map of TOPORS


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  TOPORS