TcoF overview
TcoF: UBE2L3
GeneID: 51720
Name: Ubiquitin-conjugating enzyme E2L 3, isoform CRA_a
Ensembl: ENSG00000185651
Species: Human
Class: class HC
Family: Others
Disease: 1
Go term: 26
Pathway: 7
Hallmark: 1
Super Enhancer:

chr22:21909916-21940000

Enhancer:

chr22:21996810-21997150 chr22:21997350-21998180 chr22:21822310-21822440 chr22:21822490-21822640 chr22:21822720-21823060 chr22:22248730-22249770 chr22:22112210-22113300 chr22:21679090-21679870 chr22:21680300-21680720 chr22:21771850-21773820 chr22:21821900-21822180 chr22:21823120-21823230 chr22:22087540-22089900 chr22:22085500-22087290 chr22:21823350-21823560 chr22:21910750-21911490 chr22:22024250-22024440 chr22:21941160-21943530 chr22:22020420-22022870 chr22:22305120-22307160 chr22:21640770-21641870 chr22:22055510-22057650 chr22:22190840-22193230 chr22:22294050-22294660 chr22:22314820-22316800 chr22:21933620-21935120 chr22:21947250-21948720 chr22:21948940-21949980 chr22:22185750-22187660 chr22:22007680-22008210 chr22:21837380-21838290 chr22:21258130-21260410 chr22:21272530-21274650 chr22:21274710-21275530 chr22:21275790-21276080 chr22:21290910-21292360 chr22:21292650-21292920 chr22:21294300-21295710 chr22:21587230-21589030 chr22:22057770-22058120 chr22:22125590-22127160 chr22:21943580-21944410 chr22:21944790-21947140 chr22:22145280-22147510 chr22:22189120-22190290 chr22:22203050-22205070 chr22:22213780-22214040 chr22:22214130-22214720 chr22:22214840-22215560 chr22:22215640-22216190 chr22:22217970-22218580 chr22:22323150-22324580 chr22:22376620-22378640 chr22:22424660-22425180 chr22:22043140-22045300 chr22:22120160-22122300 chr22:22197360-22197810 chr22:22198240-22199360 chr22:22200390-22202710 chr22:22280040-22281220 chr22:22335520-22335970 chr22:22336400-22336810 chr22:22439600-22441980 chr22:22281550-22282300 chr22:21956370-21956860

Promoter:

chr22:21903736-21978323

 ChIP-seq based regulatory details of UBE2L3
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of UBE2L3
 Protein-protein interaction of UBE2L3
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
UBE2L3 NEDD4 Biochemical Activity 9990509 9606 9606 BIOGRID
UBE2L3 UBE3A Biochemical Activity 9990509 9606 9606 BIOGRID
UBE2L3 ARIH1 Two-hybrid 10521492 9606 9606 BIOGRID
UBE2L3 CUL9 Two-hybrid 10521492 9606 9606 BIOGRID
UBE2L3 CBL Co-crystal Structure 10966114 9606 9606 BIOGRID
UBE2L3 CBL Affinity Capture-Western 12234920 9606 9606 BIOGRID
UBE2L3 RNF125 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 UBOX5 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 ARIH2 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 RNF144B Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 RNF113B Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 RNF144A Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 RBCK1 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 TRAF7 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 DTX3 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 CBLC Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 MID1 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 MKRN3 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 TRIM39 Two-hybrid 19549727 9606 9606 BIOGRID
UBE2L3 PARK2 Affinity Capture-Western 20089136 9606 9606 BIOGRID
UBE2L3 ATXN3 Reconstituted Complex 22081612 9606 9606 BIOGRID
UBE2L3 NFKBIA Biochemical Activity 10329681 9606 9606 BIOGRID
UBE2L3 FOS Biochemical Activity 8524278 9606 9606 BIOGRID
UBE2L3 UBE3A Reconstituted Complex 19899154 9606 9606 BIOGRID
UBE2L3 NCOA1 Affinity Capture-Western 15367689 9606 9606 BIOGRID
UBE2L3 CBL Co-crystal Structure 15062086 9606 9606 BIOGRID
UBE2L3 PARK2 Affinity Capture-Western 21694720 9606 9606 BIOGRID
UBE2L3 ARIH2 Affinity Capture-Western 22037423 9606 9606 BIOGRID
UBE2L3 RELA Biochemical Activity 14690596 9606 9606 BIOGRID
UBE2L3 SMAD7 Protein-peptide 16061177 9606 9606 BIOGRID
UBE2L3 ARIH2 Two-hybrid 19340006 9606 9606 BIOGRID
UBE2L3 USP9X Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 USP34 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 ZPR1 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 UBE2B Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 USP26 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 UBXN7 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 UBE2V2 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 YAP1 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 UCHL3 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 VDAC2 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 UBE4B Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 UBXN1 Co-fractionation 22939629 9606 9606 BIOGRID
UBE2L3 HSPA4 Biochemical Activity 14702098 9606 9606 BIOGRID
UBE2L3 UBE2L3 Biochemical Activity 20061386 9606 9606 BIOGRID
UBE2L3 UBE2L3 Reconstituted Complex 20061386 9606 9606 BIOGRID
UBE2L3 UBA1 Reconstituted Complex 25026213 9606 9606 BIOGRID
UBE2L3 ARIH1 Reconstituted Complex 10521492 9606 9606 BIOGRID
UBE2L3 ARIH2 Two-hybrid 25224329 9606 9606 BIOGRID
UBE2L3 ARIH2 Two-hybrid 16118314 9606 9606 BIOGRID
UBE2L3 UBE3A Biochemical Activity 8576257 9606 9606 BIOGRID
UBE2L3 UBE3A Reconstituted Complex 22350887 9606 9606 BIOGRID
UBE2L3 HSPE1 Co-fractionation 26344197 9606 9606 BIOGRID
UBE2L3 RAB10 Co-fractionation 26344197 9606 9606 BIOGRID
UBE2L3 SNX12 Co-fractionation 26344197 9606 9606 BIOGRID
UBE2L3 SNX3 Co-fractionation 26344197 9606 9606 BIOGRID
UBE2L3 UFM1 Co-fractionation 26344197 9606 9606 BIOGRID
UBE2L3 ITCH Biochemical Activity 26245901 9606 9606 BIOGRID
UBE2L3 UBE3A Biochemical Activity 28924046 9606 9606 BIOGRID
UBE2L3 CDKN1B Biochemical Activity 30113882 9606 9606 BIOGRID
UBE2L3 UBE3A Biochemical Activity 29263404 9606 9606 BIOGRID
UBE2L3 UBE3A Reconstituted Complex 29263404 9606 9606 BIOGRID
UBE2L3 NEDD4 Biochemical Activity 29263404 9606 9606 BIOGRID
UBE2L3 SMURF1 Biochemical Activity 29263404 9606 9606 BIOGRID
UBE2L3 SMURF2 Biochemical Activity 29263404 9606 9606 BIOGRID
UBE2L3 ANKIB1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 ARIH1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 ARIH2 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 CUL9 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HERC3 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TRIM23 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TRIM55 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HERC6 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HECTD2 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 IRF2BP1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 PIAS1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 PIAS2 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF150 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TRIM31 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 BRAP Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 CBL Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 DTX3 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HACE1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HECTD1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HECTD4 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HERC2 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HERC4 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RBCK1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HUWE1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 ITCH Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 LTN1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 MEX3A Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF114 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF168 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF19A Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF213 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF216 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF220 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF14 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF31 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TRAF6 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TRIM25 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TRIP12 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBA1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBA6 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBE3A Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBE3C Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBR4 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBR5 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF20 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 MEX3C Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 PARK2 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 HERC1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 MYCBP2 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 NEDD4L Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF170 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 UBA5 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 VPS11 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RNF19B Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 CBLB Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 RTFDC1 Reconstituted Complex 29643511 9606 9606 BIOGRID
UBE2L3 TP53 Biochemical Activity 29290977 9606 9606 BIOGRID
UBE2L3 SMURF2 Biochemical Activity 29964046 9606 9606 BIOGRID
UBE2L3 HUWE1 Biochemical Activity 29964046 9606 9606 BIOGRID
UBE2L3 PARK2 Biochemical Activity 28710279 9606 9606 BIOGRID
UBE2L3 UBE3A Biochemical Activity 15263005 9606 9606 BIOGRID
UBE2L3 ARIH1 Reconstituted Complex 29311602 9606 9606 BIOGRID
UBE2L3 RNF216 Reconstituted Complex 29311602 9606 9606 BIOGRID
UBE2L3 RNF144A Reconstituted Complex 29311602 9606 9606 BIOGRID
UBE2L3 RNF31 Reconstituted Complex 29311602 9606 9606 BIOGRID
UBE2L3 UBE3A Biochemical Activity 30097011 9606 9606 BIOGRID
UBE2L3 STUB1 Biochemical Activity 30097011 9606 9606 BIOGRID
UBE2L3 PARK2 Biochemical Activity 30446597 9606 9606 BIOGRID
UBE2L3 NEDD4L Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 NEDD4 Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 ITCH Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 HACE1 Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 UBE3C Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 SMURF2 Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 WWP1 Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 WWP2 Biochemical Activity 27182664 9606 9606 BIOGRID
UBE2L3 Trp53 Biochemical Activity 8144545 9606 10090 BIOGRID
 Annotation of UBE2L3
 TCGA cancer survival map of UBE2L3


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  UBE2L3