TcoF overview
| TcoF: | Brca1 | |
| GeneID: | 12189 | |
| Name: | Breast cancer type 1 susceptibility protein homolog | |
| Ensembl: | ENSMUSG00000017146 | |
| Species: | Mouse | |
| Class: | NA | |
| Family: | Others | |
| Disease: | -- | |
| Go-trem: | 72 | |
| Pathway: | 11 | |
| Super Enhancer: | chr11:101536511-101545195 chr11:101520579-101522894 chr11:101540778-101544289 chr11:101518949-101519512 chr11:101518327-101520481 chr11:101525173-101526761 chr11:101516952-101520323 chr11:101524661-101527279 chr11:101519222-101519929 |
|
| Enhancer: |
chr11:101076610-101078300 chr11:101078430-101078550 chr11:101078670-101079960 chr11:101080030-101087700 chr11:101108450-101108890 chr11:101109000-101109120 chr11:101115120-101115340 chr11:101116310-101117320 chr11:101117410-101118190 chr11:101118260-101119210 chr11:101125300-101125580 chr11:101125730-101126390 chr11:101136180-101136280 chr11:101139760-101140020 chr11:101148260-101148710 chr11:101161280-101163040 chr11:101163170-101163440 chr11:101177800-101178490 chr11:101187990-101189650 chr11:101189940-101190130 chr11:101190260-101190510 chr11:101193850-101197030 chr11:101200740-101205990 chr11:101215500-101219020 chr11:101259050-101268150 chr11:101278540-101278660 chr11:101286920-101289220 chr11:101303770-101304030 chr11:101304110-101304810 chr11:101304980-101306530 chr11:101309930-101317870 chr11:101330330-101331320 chr11:101331430-101332030 chr11:101401340-101403380 chr11:101411400-101413080 chr11:101413890-101413960 chr11:101414260-101415300 chr11:101417600-101420830 chr11:101560820-101563020 chr11:101616680-101618900 chr11:101619060-101621280 chr11:101667050-101669750 chr11:101689980-101694580 chr11:101285580-101285920 chr11:101400100-101401290 chr11:101415410-101417120 chr11:101547700-101550180 chr11:101645940-101646420 chr11:101239310-101242640 chr11:101247060-101249580 chr11:101249770-101253350 chr11:101263940-101265920 chr11:101306640-101306750 chr11:101323870-101324220 chr11:101444010-101444870 chr11:101445090-101445750 chr11:101412800-101413080 chr11:101304110-101304290 chr11:101338310-101341490 chr11:101478260-101479260 chr11:101526950-101527250 chr11:101550660-101551450 chr11:101556540-101558920 chr11:101548550-101549530 chr11:101303830-101304030 chr11:101414260-101415090 chr11:101178700-101178930 chr11:101179040-101180760 chr11:101286920-101288200 chr11:101443630-101443930 chr11:101526950-101527860 chr11:101594500-101595460 chr11:101595550-101595840 chr11:101415410-101416440 chr11:101294180-101294760 chr11:101412050-101413080 chr11:101601220-101601970 chr11:101594500-101595410 chr11:101415410-101415660 chr11:101309930-101311190 chr11:101526950-101527210 chr11:101594500-101595440 chr11:101329750-101330240 chr11:101330330-101330590 chr11:101131000-101131680 chr11:101284760-101285090 chr11:101293510-101294760 chr11:101323210-101323510 chr11:101323600-101323700 chr11:101332160-101332370 chr11:101337650-101342710 chr11:101559960-101563690 chr11:101645320-101645540 chr11:101645630-101645830 chr11:101699050-101706540 chr11:101750050-101751760 chr11:101415410-101415940 chr11:101547960-101550020 chr11:101235040-101235900 chr11:101236010-101236400 chr11:101237410-101237600 chr11:101412010-101413080 chr11:101526950-101527320 chr11:101414260-101414780 chr11:101414260-101414600 chr11:101317320-101317870 chr11:101445820-101446780 chr11:101187990-101188330 chr11:101194480-101197030 chr11:101312090-101314170 chr11:101338460-101341760 chr11:101414260-101414900 chr11:101451300-101451640 chr11:101534160-101536370 chr11:101556280-101559900 chr11:101633260-101634920 chr11:101750500-101751660 chr11:101752020-101753840 chr11:101177800-101178300 chr11:101412200-101413080 chr11:101414260-101415250 chr11:101594500-101595270 chr11:101304110-101304670 chr11:101411930-101413080 chr11:101556560-101559100 chr11:101285020-101285090 chr11:101285190-101285290 chr11:101285350-101285460 chr11:101286920-101287400 chr11:101306640-101306700 chr11:101309930-101310840 chr11:101412640-101413080 chr11:101414260-101414700 chr11:101556300-101558900 chr11:101594500-101595060 chr11:101601160-101601970 chr11:101632810-101633000 chr11:101633070-101633190 chr11:101644180-101645280 chr11:101557490-101558280 chr11:101338330-101341780 chr11:101478080-101479260 chr11:101411990-101413080 chr11:101415410-101416280 chr11:101412470-101413080 chr11:101414260-101414910 chr11:101526950-101527360 chr11:101414260-101414950 chr11:100946510-100946590 chr11:100946660-100946840 chr11:100950630-100950980 chr11:101052030-101052420 chr11:101059620-101060570 chr11:101060690-101061250 chr11:101085310-101087700 chr11:101119360-101120080 chr11:101124200-101125080 chr11:101137700-101137790 chr11:101137990-101138140 chr11:101138230-101138340 chr11:101140790-101141540 chr11:101178520-101178640 chr11:101179040-101179900 chr11:101284790-101285090 chr11:101286920-101288690 chr11:101323060-101323510 chr11:101410420-101413080 chr11:101529140-101534090 chr11:101534130-101537200 chr11:101595550-101596240 chr11:101396910-101401290 chr11:101309930-101314580 chr11:101316450-101317870 chr11:101321590-101321690 chr11:101322430-101323510 chr11:101529140-101535930 chr11:101415410-101416340 chr11:101414260-101414470 chr11:101330330-101330940 chr11:101340060-101343240 chr11:101702800-101704750 chr11:101415410-101415480 chr11:101534130-101535510 chr11:101330330-101330980 chr11:101304110-101304340 chr11:101323340-101323510 chr11:101330330-101330580 chr11:101338250-101342740 chr11:101478170-101479190 chr11:101526950-101527180 chr11:101691450-101691830 chr11:101645940-101646390 chr11:101414260-101415100 chr11:101444010-101444120 chr11:101526950-101527300 chr11:101179040-101179930 chr11:101309930-101310950 chr11:101338270-101343360 chr11:101428570-101429710 chr11:101429920-101430560 chr11:101472220-101472400 chr11:101472490-101477090 chr11:101477270-101479260 chr11:101529140-101532800 chr11:101533140-101546600 chr11:101594500-101595420 chr11:101638460-101645280 chr11:101415410-101416320 chr11:101304110-101304690 chr11:101446180-101446810 chr11:101453600-101455960 chr11:101080800-101084800 chr11:101085200-101087700 chr11:101124200-101124880 chr11:101140790-101144700 chr11:101144780-101145030 chr11:101145200-101146070 chr11:101161600-101163040 chr11:101284800-101285090 chr11:101286920-101290200 chr11:101309930-101311000 chr11:101330330-101330560 chr11:101412000-101413080 chr11:101417600-101419600 chr11:101426140-101427010 chr11:101427090-101427500 chr11:101445820-101446800 chr11:101526950-101527800 chr11:101533600-101535420 chr11:101644400-101645280 chr11:101669800-101672000 chr11:101304980-101306400 chr11:101323200-101323510 chr11:101330330-101330450 chr11:101337600-101342800 chr11:101414260-101414790 chr11:101086840-101087700 chr11:101194920-101196300 chr11:101278200-101278410 chr11:101412690-101413080 chr11:101478150-101479260 chr11:101557050-101558490 chr11:101645010-101645280 chr11:101690800-101692700 chr11:101728570-101729890 chr11:101750510-101751700 chr11:101751830-101753840 chr11:101662510-101664020 chr11:101414960-101415300 chr11:101526950-101527200 chr11:101557290-101558510 chr11:101633270-101634000 chr11:101178700-101178800 chr11:101284970-101285090 chr11:101475530-101477090 chr11:101477270-101479020 chr11:101556530-101559690 chr11:101415410-101415550 chr11:101131000-101131610 chr11:101179040-101179700 chr11:101304110-101304770 chr11:101476120-101477090 chr11:101526950-101527140 chr11:101556540-101559570 chr11:101617840-101618900 chr11:101619060-101619640 chr11:101645330-101645540 chr11:101691060-101692510 chr11:101717370-101718010 chr11:101728550-101729740 chr11:101730810-101732220 chr11:101734480-101735380 chr11:101740750-101744300 chr11:101745890-101748810 chr11:101415410-101415520 chr11:101548060-101549810 chr11:101529140-101537210 chr11:101556610-101559380 chr11:101559860-101563650 chr11:101548060-101549900 chr11:101107880-101108360 chr11:101177800-101178140 chr11:101286920-101287950 chr11:101309930-101310850 chr11:101556650-101558560 chr11:101561360-101562640 chr11:101618290-101618900 chr11:101633850-101634430 chr11:101691110-101691880 chr11:101703730-101704080 chr11:101548550-101549620 chr11:101577420-101582740 chr11:101633260-101634630 chr11:101644430-101645280 chr11:101665490-101670380 chr11:101682870-101706400 chr11:101740750-101753990 chr11:100684000-100686090 chr11:100709040-100711710 chr11:100720890-100721790 chr11:100721890-100722640 chr11:100722770-100723030 chr11:100746480-100748110 chr11:100750070-100750790 chr11:100757720-100759620 chr11:100767240-100768930 chr11:100776360-100776840 chr11:100788440-100789540 chr11:100852450-100852860 chr11:100854780-100856140 chr11:100948840-100949060 chr11:100949100-100949540 chr11:100978900-100980850 chr11:100981550-100981860 chr11:100999860-101000410 chr11:101081860-101083450 chr11:101086640-101087700 chr11:101119660-101120080 chr11:101131000-101131570 chr11:101218580-101219020 chr11:101309930-101311380 chr11:101312540-101314220 chr11:101329750-101329990 chr11:101532420-101533010 chr11:101414260-101415240 chr11:101330330-101330570 chr11:101415410-101415670 chr11:101087140-101087700 chr11:101107880-101108150 chr11:101179040-101179590 chr11:101286920-101287180 chr11:101294080-101294760 chr11:101304980-101305310 chr11:101315610-101317140 chr11:101322960-101323510 chr11:101338390-101341820 chr11:101411890-101413080 chr11:101594500-101594960 chr11:101617190-101618900 chr11:101619060-101620880 chr11:101632900-101633000 chr11:101643610-101645280 chr11:101548010-101549910 chr11:101414260-101414760 chr11:101455200-101455630 chr11:101445820-101446650 chr11:100991150-100992550 chr11:101746390-101748830 chr11:101322840-101323510 chr11:101417600-101418810 chr11:101556460-101563780 chr11:101572910-101576050 chr11:101617020-101618900 chr11:101619060-101620960 chr11:101580490-101581980 chr11:101286920-101287010 chr11:101414260-101414740 chr11:101284960-101285090 chr11:101304110-101304730 chr11:101322300-101323510 chr11:101331430-101331980 chr11:101534280-101535030 chr11:101556670-101558850 chr11:101561930-101562560 chr11:101303770-101303970 chr11:101414260-101414650 chr11:101286920-101287260 chr11:101304110-101304450 chr11:101323870-101324190 chr11:101412180-101413080 chr11:101472490-101474100 chr11:101526950-101527460 chr11:101534350-101534930 chr11:101594500-101594760 chr11:101444010-101444660 chr11:101594500-101594880 chr11:101745500-101748500 chr11:101549050-101549800 chr11:101304110-101304680 chr11:101309930-101310220 chr11:101558130-101559320 chr11:101594500-101594800 chr11:101746410-101748300 chr11:101412680-101413080 chr11:101414260-101414610 chr11:101304110-101304640 chr11:101414260-101414820 chr11:101444010-101444250 chr11:101560670-101563490 chr11:101574040-101575990 chr11:101331490-101332030 chr11:101339650-101342800 chr11:101429920-101430210 chr11:101086520-101087700 chr11:101193850-101196380 chr11:101239600-101241290 chr11:101247760-101248790 chr11:101249860-101250800 chr11:101251280-101253030 chr11:101261360-101262620 chr11:101263880-101265960 chr11:101560900-101562580 chr11:101195790-101196320 chr11:101304110-101304740 chr11:101340310-101341000 chr11:101412850-101413080 chr11:101414260-101414550 chr11:101429920-101430340 chr11:101633260-101634430 chr11:101581240-101581860 |
|
| Promoter: |
chr11:101549955-101553955 |
ChIP-seq based regulatory details of Brca1
| Sample ID | Experiment target | Biosample term name | Cell type | Tissue type | Source |
|---|---|---|---|---|---|
| TcoF_01_20836 | Brca1 | None | B Lymphocyte | Spleen | Cistrome |
| TcoF_01_20835 | Brca1 | None | B Lymphocyte | Spleen | Cistrome |
| TcoF_01_20834 | Brca1 | None | B Lymphocyte | Spleen | Cistrome |
| TcoF_01_20833 | Brca1 | None | B Lymphocyte | Spleen | Cistrome |
| TcoF_01_20832 | Brca1 | None | B Lymphocyte | Spleen | Cistrome |
Downstream target genes of Brca1
Protein-protein interaction of Brca1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| Brca1 | Brca2 | Two-hybrid | 20211142 | 10090 | 10090 | BIOGRID |
| Brca1 | Ewsr1 | Two-hybrid | 20211142 | 10090 | 10090 | BIOGRID |
| Brca1 | Hoxa2 | Two-hybrid | 20211142 | 10090 | 10090 | BIOGRID |
| Brca1 | Hoxc12 | Two-hybrid | 20211142 | 10090 | 10090 | BIOGRID |
| Brca1 | Tcf3 | Two-hybrid | 20211142 | 10090 | 10090 | BIOGRID |
| Brca1 | Olig1 | Two-hybrid | 20211142 | 10090 | 10090 | BIOGRID |
| Brca1 | Atr | Affinity Capture-Western | 15589157 | 10090 | 10090 | BIOGRID |
| Brca1 | Smarca2 | Affinity Capture-Western | 15574597 | 10090 | 10090 | BIOGRID |
| Brca1 | Nbn | Co-localization | 12792649 | 10090 | 10090 | BIOGRID |
| Brca1 | Acot7 | Affinity Capture-Western | 22034435 | 10090 | 10090 | BIOGRID |
| Brca1 | Brca1 | Biochemical Activity | 19088202 | 10090 | 10090 | BIOGRID |
| Brca1 | UBE2D3 | Reconstituted Complex | 19088202 | 10090 | 9606 | BIOGRID |
| Brca1 | Esr1 | Affinity Capture-Western | 16807234 | 10090 | 10090 | BIOGRID |
| Brca1 | Jun | Affinity Capture-Western | 16807234 | 10090 | 10090 | BIOGRID |
| Brca1 | Etv4 | Affinity Capture-Western | 16807234 | 10090 | 10090 | BIOGRID |
| Brca1 | UBC | Affinity Capture-Western | 10500182 | 10090 | 9606 | BIOGRID |
| Brca1 | Ezh2 | Affinity Capture-Western | 23624935 | 10090 | 10090 | BIOGRID |
| Brca1 | Suz12 | Affinity Capture-Western | 23624935 | 10090 | 10090 | BIOGRID |
| Brca1 | Pou2f1 | Affinity Capture-Western | 17700520 | 10090 | 10090 | BIOGRID |
| Brca1 | Acaca | Affinity Capture-Western | 24565757 | 10090 | 10090 | BIOGRID |
| Brca1 | BAD | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | BARD1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | BLMH | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | CETN2 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | NDST1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | MSH5 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | MYH6 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | ABCE1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | UXT | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | DNPH1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | SMCHD1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | PRPF38A | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | SCLT1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Brca1 | Trp53bp1 | Phenotypic Suppression | 23657012 | 10090 | 10090 | BIOGRID |
| Brca1 | Kntc1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Brca1 | Taf5l | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
Annotation of Brca1
Expression of Brca1
Disease information of Brca1