TcoF overview
| TcoF: | Pten | |
| GeneID: | 19211 | |
| Name: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | |
| Ensembl: | ENSMUSG00000013663 | |
| Species: | Mouse | |
| Class: | class 2 | |
| Family: | Others | |
| Disease: | 14 | |
| Go-trem: | 144 | |
| Pathway: | 30 | |
| Super Enhancer: | chr19:32925913-32961637 chr19:32898730-32911558 chr19:32869126-32869695 chr19:32778157-32793118 chr19:32903403-32912984 chr19:32950228-32951469 chr19:32759699-32761280 chr19:32882464-32886889 chr19:32778378-32806261 chr19:32901305-32907685 chr19:32939373-32941314 chr19:32760552-32761322 chr19:32956519-32957297 chr19:32778430-32788778 chr19:32939896-32953940 chr19:32904208-32906353 chr19:32901878-32906315 chr19:32939982-32940720 chr19:32874021-32886091 chr19:32956559-32957431 chr19:32830549-32845362 chr19:32883871-32886619 chr19:32925252-32938552 chr19:32861591-32869819 chr19:32904188-32904887 chr19:32760140-32761080 chr19:32789716-32790322 chr19:32955757-32975504 chr19:32822624-32823465 chr19:32912830-32913992 chr19:32867238-32868128 chr19:32793882-32794418 chr19:32955643-32961134 chr19:32912326-32913521 chr19:32905763-32906460 chr19:32868658-32869759 chr19:32901281-32906531 chr19:32960094-32961066 chr19:32901070-32901907 chr19:32789587-32790270 chr19:32939866-32961681 chr19:32901315-32907632 chr19:32804634-32805519 chr19:32789652-32790251 chr19:32901016-32906631 chr19:32925498-32926566 chr19:32955705-32979083 chr19:32903263-32907416 chr19:32885146-32886211 chr19:32952821-32964296 chr19:32901979-32907691 chr19:32932704-32933918 chr19:32787419-32788753 chr19:32874059-32874764 chr19:32901321-32906657 chr19:32960301-32960953 chr19:32933465-32934088 chr19:32952440-32964431 chr19:32868433-32870381 chr19:32901392-32907762 chr19:32847933-32848808 chr19:32760506-32761099 chr19:32939600-32961598 chr19:32904202-32907650 chr19:32868961-32869870 chr19:32788069-32788690 chr19:32760633-32761092 chr19:32901724-32906600 chr19:32901489-32907536 chr19:32952421-32964766 chr19:32905280-32907567 chr19:32826233-32827012 chr19:32874108-32874807 chr19:32935272-32999432 chr19:32903437-32913974 chr19:32789123-32794767 chr19:32887021-32887853 chr19:32831776-32833035 chr19:32861941-32863074 chr19:32956039-32964392 chr19:32867110-32869029 chr19:32903558-32906815 chr19:32935464-32936048 chr19:32904526-32904980 chr19:32901394-32926204 chr19:32949996-32979005 chr19:32903399-32907140 chr19:32933456-32936325 chr19:32792144-32793192 chr19:32869082-32869901 chr19:32847919-32848501 |
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| Enhancer: |
chr19:32246300-32259680 chr19:32268520-32278000 chr19:32339920-32345450 chr19:32345600-32352750 chr19:32370750-32381900 chr19:32382180-32386700 chr19:32387150-32398180 chr19:32410680-32423180 chr19:32446220-32454520 chr19:32455580-32462700 chr19:32463860-32464190 chr19:32490780-32494380 chr19:32580000-32582650 chr19:32621440-32623180 chr19:32623250-32627600 chr19:32641180-32642450 chr19:32749300-32751200 chr19:32853950-32867030 chr19:32867080-32868740 chr19:32892550-32894330 chr19:32900650-32911060 chr19:32942130-32945080 chr19:32965510-32968160 chr19:32994660-33005050 chr19:33006780-33019950 chr19:33050820-33057550 chr19:33067900-33069880 chr19:33077920-33079290 chr19:33084180-33089800 chr19:33270950-33272320 chr19:32912140-32920680 chr19:33291300-33293200 chr19:32786370-32786750 chr19:33027900-33028110 chr19:32460810-32462700 chr19:33054220-33055930 chr19:33013730-33015810 chr19:32786270-32786750 chr19:33034300-33035430 chr19:32786200-32786750 chr19:32786180-32786750 chr19:32786450-32786750 chr19:32461280-32462700 chr19:33027360-33028620 chr19:32799960-32803300 chr19:32900650-32901980 chr19:33030180-33032300 chr19:33034020-33036590 chr19:33037240-33039670 chr19:32700920-32702350 chr19:32785020-32786750 chr19:32539060-32540140 chr19:32785530-32786750 chr19:33000440-33001040 chr19:33010060-33010850 chr19:33127730-33128580 chr19:32785190-32786750 chr19:32785430-32786750 chr19:32800370-32802680 chr19:32711770-32712740 chr19:32800530-32801990 chr19:32867910-32868740 chr19:33009900-33010690 chr19:33024790-33026200 chr19:33030560-33032410 chr19:33038460-33039360 chr19:33109760-33111770 chr19:33116810-33118030 chr19:33127290-33128440 chr19:32700850-32701890 chr19:32711750-32712650 chr19:32786190-32786750 chr19:32462540-32462700 chr19:32786390-32786750 chr19:32252510-32258040 chr19:32259810-32264460 chr19:32458020-32462700 chr19:32859260-32867030 chr19:33013300-33015680 chr19:32799960-32804200 chr19:32867180-32868740 chr19:32800840-32802350 chr19:33031460-33032610 chr19:32785230-32786750 chr19:32799960-32804620 chr19:32867170-32868740 chr19:32785890-32786750 chr19:32800580-32802310 chr19:32461230-32462700 chr19:32800780-32802670 chr19:32786060-32786750 chr19:32252550-32258100 chr19:32269280-32272960 chr19:32413170-32420450 chr19:32711750-32712740 chr19:32712880-32713400 chr19:32726890-32728870 chr19:32273520-32276830 chr19:32334580-32342580 chr19:32460510-32462700 chr19:32561040-32563320 chr19:32571360-32572870 chr19:32573000-32574320 chr19:32584070-32586000 chr19:32726970-32728870 chr19:33030340-33032450 chr19:32641490-32642520 chr19:32943760-32944360 chr19:33009940-33010880 chr19:33034890-33035580 chr19:32461180-32462700 chr19:32414290-32422180 chr19:32708490-32711520 chr19:32867080-32867630 chr19:33014150-33015670 chr19:32786160-32786750 chr19:32801320-32801840 chr19:32581550-32582670 chr19:32786210-32786750 chr19:32799960-32804080 chr19:32584610-32585170 chr19:32673360-32674570 chr19:32675500-32676250 chr19:32680990-32682200 chr19:32867080-32867550 chr19:32417200-32423180 chr19:32433000-32438600 chr19:32450200-32454600 chr19:32460860-32462700 chr19:32568600-32572870 chr19:32580200-32587000 chr19:32645800-32648100 chr19:32673360-32680000 chr19:32785400-32786750 chr19:33032530-33039630 chr19:32684160-32686590 chr19:32786120-32786750 chr19:32629570-32630390 chr19:32786010-32786750 chr19:32629100-32630410 chr19:32678490-32682310 chr19:32786070-32786750 chr19:32867170-32867540 chr19:33000270-33001050 chr19:32462300-32462700 chr19:32786140-32786750 chr19:32867170-32867470 chr19:32786430-32786750 chr19:32785520-32786750 chr19:32965890-32967950 chr19:33034970-33037860 chr19:33081710-33090320 chr19:33103460-33105880 chr19:32568450-32572870 chr19:32866370-32867030 chr19:32867080-32867880 chr19:33010030-33010800 chr19:32785140-32786750 chr19:32942780-32944770 chr19:32800950-32802550 chr19:32786300-32786750 chr19:32679440-32681700 chr19:33007920-33016170 chr19:32785800-32786750 chr19:33024710-33025680 chr19:32785790-32786750 chr19:33013910-33015210 chr19:32459930-32462700 chr19:32570600-32572870 chr19:32573000-32575270 chr19:32645600-32648100 chr19:32673360-32681620 chr19:32861850-32867030 chr19:32625630-32627240 chr19:32678510-32679760 chr19:32786170-32786750 chr19:32786240-32786750 chr19:32460910-32462700 chr19:32647430-32648020 chr19:32674390-32676580 chr19:32867180-32867400 chr19:33104590-33105340 chr19:32813930-32814180 chr19:32478230-32485550 chr19:33000120-33001340 chr19:33126960-33128630 chr19:32461220-32462700 chr19:32621840-32622960 chr19:32786540-32786750 chr19:32900790-32901390 chr19:32943700-32944160 chr19:33037700-33039210 chr19:32700780-32702160 chr19:32786130-32786750 chr19:32625920-32626990 chr19:32786400-32786750 chr19:32800200-32802380 chr19:33030070-33033790 chr19:32378210-32380180 chr19:32383170-32384290 chr19:32711360-32711520 chr19:32786080-32786750 chr19:32800990-32801790 |
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| Promoter: |
chr19:32755576-32759576 |
ChIP-seq based regulatory details of Pten
| Sample ID | Experiment target | Biosample term name | Cell type | Tissue type | Source |
|---|
Downstream target genes of Pten
Protein-protein interaction of Pten
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| Pten | Xiap | Affinity Capture-Western | 19473982 | 10090 | 10090 | BIOGRID |
| Pten | Fbxw7 | Synthetic Haploinsufficiency | 22513362 | 10090 | 10090 | BIOGRID |
| Pten | Ndfip1 | Affinity Capture-Western | 23012657 | 10090 | 10090 | BIOGRID |
| Pten | Trp53 | Affinity Capture-Western | 18332125 | 10090 | 10090 | BIOGRID |
| Pten | EIF4B | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | IGHG3 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | MTRR | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | RAD51 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | LRP8 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | BRAP | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | MPZL1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | DCAF13 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | ITSN2 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | CCDC186 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | SERINC1 | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | NCKAP5L | Affinity Capture-MS | 26496610 | 10090 | 9606 | BIOGRID |
| Pten | Braf | Positive Genetic | 27184621 | 10090 | 10090 | BIOGRID |
| Pten | Dlg1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Eef1a2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Ptk2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Ptk2b | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Usp7 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Chgb | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Csnk2a2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | G3bp2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Magi2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Ppp3ca | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Slc9a3r1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Slc9a3r2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Arhgap26 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Pten | Amph | Affinity Capture-MS | 31291551 | 10090 | 10090 | BIOGRID |
| Pten | Bin1 | Affinity Capture-MS | 31291551 | 10090 | 10090 | BIOGRID |
| Pten | Ap2b1 | Affinity Capture-MS | 31291551 | 10090 | 10090 | BIOGRID |
| Pten | Amph | Reconstituted Complex | 31291551 | 10090 | 10090 | BIOGRID |
| Pten | Bin1 | Reconstituted Complex | 31291551 | 10090 | 10090 | BIOGRID |
| Pten | Amph | Affinity Capture-Western | 31291551 | 10090 | 10090 | BIOGRID |
Annotation of Pten
Expression of Pten
Disease information of Pten