TcoF overview
| TcoF: | Sqstm1 | |
| GeneID: | 18412 | |
| Name: | Sequestosome-1 | |
| Ensembl: | ENSMUSG00000015837 | |
| Species: | Mouse | |
| Class: | class 1 | |
| Family: | Others | |
| Disease: | 1 | |
| Go-trem: | 49 | |
| Pathway: | 17 | |
| Super Enhancer: | chr11:50216453-50219133 chr11:50204794-50206502 chr11:50196790-50208453 chr11:50215230-50216196 chr11:50215101-50219289 chr11:50214696-50219018 chr11:50193612-50202195 chr11:50194899-50200277 chr11:50212941-50213587 chr11:50215380-50219617 chr11:50216717-50217580 chr11:50201538-50201992 |
|
| Enhancer: |
chr11:49568000-49569720 chr11:49625300-49625960 chr11:49945050-49948950 chr11:49988450-49990110 chr11:50005900-50007700 chr11:50010590-50011120 chr11:50011200-50013030 chr11:50014440-50015900 chr11:50016090-50016310 chr11:50016530-50018710 chr11:50019080-50019520 chr11:50020800-50020900 chr11:50021130-50021320 chr11:50021410-50024050 chr11:50039240-50040230 chr11:50044360-50044460 chr11:50044600-50044690 chr11:50048600-50049960 chr11:50050210-50050510 chr11:50050600-50050690 chr11:50050760-50050840 chr11:50050940-50051830 chr11:50096080-50105220 chr11:50191300-50191790 chr11:50193120-50193320 chr11:50193460-50194960 chr11:50195090-50196030 chr11:50196210-50196300 chr11:50196560-50196680 chr11:50196810-50197180 chr11:50197240-50197330 chr11:50197420-50198140 chr11:50254610-50256720 chr11:50267060-50269150 chr11:50444380-50453100 chr11:50453250-50459070 chr11:50466800-50468500 chr11:50477280-50481490 chr11:50508380-50510680 chr11:50019600-50020660 chr11:49887480-49887730 chr11:49945050-49945590 chr11:49947760-49948030 chr11:49975880-49976190 chr11:50023600-50024050 chr11:49945050-49946390 chr11:49988450-49988940 chr11:50049010-50049960 chr11:50072330-50074420 chr11:49795250-49795630 chr11:49945050-49945510 chr11:49988450-49988760 chr11:50023690-50024050 chr11:49945050-49945170 chr11:49988450-49988950 chr11:50023250-50024050 chr11:50235450-50236100 chr11:50191730-50191790 chr11:49945050-49945610 chr11:50023400-50024050 chr11:49945050-49945490 chr11:49988450-49988680 chr11:50023300-50024050 chr11:50039240-50039450 chr11:49945050-49946690 chr11:49946910-49949320 chr11:49988450-49989710 chr11:50022050-50024050 chr11:50039240-50040030 chr11:49945050-49946320 chr11:49988450-49989230 chr11:50023180-50024050 chr11:50389180-50390870 chr11:50022480-50024050 chr11:50191920-50192960 chr11:49791980-49792990 chr11:49795250-49798010 chr11:49945050-49946510 chr11:49947670-49948250 chr11:49988450-49989110 chr11:50023210-50024050 chr11:50093590-50094620 chr11:49592060-49593170 chr11:49746870-49754040 chr11:49886000-49891100 chr11:49907320-49909270 chr11:49912840-49918050 chr11:49945050-49946700 chr11:49958070-49958520 chr11:49958750-49959600 chr11:49959860-49961520 chr11:49961730-49962310 chr11:49988450-49990100 chr11:50044070-50044180 chr11:50045280-50045520 chr11:50045630-50045740 chr11:50045880-50046060 chr11:50046570-50046770 chr11:50046880-50046960 chr11:50047150-50047580 chr11:50047830-50047910 chr11:50048020-50048100 chr11:50449090-50454050 chr11:50466360-50469770 chr11:50480760-50481490 chr11:49774100-49774650 chr11:49743360-49760800 chr11:49945050-49946570 chr11:49988450-49989690 chr11:50022070-50024050 chr11:50235020-50235130 chr11:50235300-50236560 chr11:50303880-50306340 chr11:50216380-50217950 chr11:49791980-49792300 chr11:49797080-49798040 chr11:49852220-49852880 chr11:49945050-49946260 chr11:49988450-49990010 chr11:49996140-49997500 chr11:50049640-50049960 chr11:50050940-50051660 chr11:49945050-49945810 chr11:49945050-49945330 chr11:49844170-49858200 chr11:49860660-49865690 chr11:49946930-49949320 chr11:50049310-50049960 chr11:50097880-50105220 chr11:49919850-49923970 chr11:49988450-49989340 chr11:50023360-50024050 chr11:50204770-50205520 chr11:49795250-49796350 chr11:49945050-49945990 chr11:49988450-49989140 chr11:50023260-50024050 chr11:50049400-50049960 chr11:49945050-49946160 chr11:49988450-49988870 chr11:50049420-50049960 chr11:50092360-50095180 chr11:50203870-50205520 chr11:50235300-50237580 chr11:49945050-49946610 chr11:49988450-49989130 chr11:50023280-50024050 chr11:50049480-50049960 chr11:49945050-49946100 chr11:50039240-50040100 chr11:49988450-49989040 chr11:50023500-50024050 chr11:50234930-50235130 chr11:50235300-50235670 chr11:49988450-49988980 chr11:50023190-50024050 chr11:49793720-49794870 chr11:50230800-50233120 chr11:50233990-50235130 chr11:50235300-50237240 chr11:49576310-49580800 chr11:50233220-50233870 chr11:49792020-49792990 chr11:49851830-49853060 chr11:49945050-49949320 chr11:49988450-49989440 chr11:50022000-50024050 chr11:50235300-50236950 chr11:49988450-49988550 chr11:50169270-50169380 chr11:49921590-49922880 chr11:49945050-49945930 chr11:49988450-49989320 chr11:50023230-50024050 chr11:49912380-49912740 chr11:49945050-49946620 chr11:49947320-49949290 chr11:49960300-49961520 chr11:49961730-49963200 chr11:49963410-49964200 chr11:49988450-49989220 chr11:50019080-50019320 chr11:50022640-50024050 chr11:50154980-50156600 chr11:50204540-50205520 chr11:50255080-50255500 chr11:50215880-50217940 chr11:49945050-49945410 chr11:49988450-49989250 chr11:50023220-50024050 chr11:50039280-50040150 chr11:49945050-49945220 chr11:50023810-50024050 chr11:50098340-50105220 chr11:49567680-49570420 chr11:49945050-49946250 chr11:49989580-49990110 chr11:49996200-49997280 chr11:50011200-50012310 chr11:50023320-50024050 chr11:50078840-50079090 chr11:50116410-50117390 chr11:50169270-50169560 chr11:49576480-49578800 chr11:49921620-49923080 chr11:50215690-50217650 chr11:49945050-49946600 chr11:49988450-49989470 chr11:50021800-50024050 chr11:50049200-50049960 chr11:50149170-50151600 chr11:50023820-50024050 chr11:50099200-50105220 chr11:49740130-49741660 chr11:49945050-49946070 chr11:50023670-50024050 chr11:50050940-50051390 chr11:49740080-49740950 chr11:49945050-49945270 chr11:50049530-50049960 chr11:50235300-50235840 chr11:50459760-50460150 chr11:49945050-49946790 chr11:50023200-50024050 chr11:50049140-50049960 chr11:50235050-50235130 chr11:49945050-49946490 chr11:49988450-49989880 chr11:50049630-50049960 chr11:49947250-49948460 chr11:49945050-49946290 chr11:49947630-49948700 chr11:49922460-49922800 chr11:49945050-49946580 chr11:49966340-49968580 chr11:49968700-49970240 chr11:49999010-50001670 chr11:50072330-50073420 chr11:50377920-50380460 chr11:49593460-49594350 chr11:49595600-49596190 chr11:49732490-49733660 chr11:49739210-49740470 chr11:49778300-49779860 chr11:49795250-49796780 chr11:49851790-49853140 chr11:49860660-49862780 chr11:49894840-49895990 chr11:49982620-49982960 chr11:49988450-49990090 chr11:50023160-50024050 chr11:50099640-50101000 chr11:50169270-50169510 chr11:50235300-50236820 chr11:49578210-49581300 chr11:50149170-50151420 chr11:49945050-49945460 chr11:49966860-49968580 chr11:49968700-49969390 chr11:49945050-49946350 chr11:49988450-49989350 chr11:50049290-50049960 chr11:50050940-50051110 chr11:49795250-49797660 chr11:49915150-49918050 chr11:49945050-49946770 chr11:49949180-49949320 chr11:49975610-49976980 chr11:49920510-49923920 chr11:49946640-49949320 chr11:49744040-49746060 chr11:49747250-49748740 chr11:49945050-49946450 chr11:49988450-49989300 chr11:50022780-50024050 chr11:50049110-50049960 chr11:50050940-50051700 chr11:50255030-50256420 chr11:50305840-50306340 chr11:50384830-50385460 chr11:49945050-49945860 chr11:49988450-49988820 chr11:50023390-50024050 chr11:50010640-50011080 chr11:50023590-50024050 chr11:50380100-50380530 chr11:49796410-49798860 chr11:49851610-49852960 chr11:49945940-49949220 chr11:49988450-49989100 chr11:50098720-50100950 chr11:50169270-50170060 chr11:49921590-49923410 chr11:50023680-50024050 chr11:49975610-49976760 chr11:49945050-49946820 chr11:49946950-49948530 chr11:49960520-49961520 chr11:49963410-49963750 chr11:50086120-50094850 chr11:49921520-49924050 chr11:50216520-50217950 chr11:49945050-49945530 chr11:49988450-49988690 chr11:50023470-50024050 chr11:50039240-50039510 chr11:49945050-49946090 chr11:49796450-49796840 chr11:49852650-49853260 chr11:49945050-49945600 chr11:49988450-49988640 chr11:49945050-49945750 chr11:50023270-50024050 chr11:50050940-50051440 chr11:50235520-50236330 chr11:49988450-49988630 chr11:50235390-50235900 chr11:49945050-49945680 chr11:49988450-49988840 chr11:50039240-50039420 chr11:50049810-50049960 chr11:50193460-50194160 chr11:50235300-50236120 chr11:49915780-49918050 chr11:49988450-49989370 chr11:50092150-50095230 chr11:50099000-50105220 chr11:49796320-49796900 chr11:49797110-49797790 chr11:49945050-49946550 chr11:49946970-49948460 chr11:49988450-49988730 chr11:50023240-50024050 chr11:50049710-50049960 chr11:50093510-50094640 chr11:49921700-49922790 chr11:49988450-49989160 chr11:50049590-50049960 chr11:50093550-50093910 chr11:50099980-50100850 chr11:49988450-49988810 chr11:50235370-50235670 chr11:49963410-49963680 chr11:49988450-49988710 chr11:50039240-50039590 chr11:50049190-50049960 chr11:50023570-50024050 chr11:50204310-50205520 chr11:49945050-49946180 chr11:49960470-49961520 chr11:49968120-49968580 chr11:49968700-49968790 chr11:49988450-49988790 chr11:50023170-50024050 chr11:50051040-50051830 chr11:50451520-50452470 chr11:49945050-49945570 chr11:49988450-49988850 chr11:50023010-50024050 chr11:50039240-50039480 chr11:50050940-50051380 chr11:50080510-50080840 chr11:50204650-50205170 chr11:50235300-50235910 chr11:50379330-50379770 |
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| Promoter: |
chr11:50208790-50212790 |
ChIP-seq based regulatory details of Sqstm1
| Sample ID | Experiment target | Biosample term name | Cell type | Tissue type | Source |
|---|
Downstream target genes of Sqstm1
Protein-protein interaction of Sqstm1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| Sqstm1 | Ntrk1 | Affinity Capture-Western | 18598672 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Trim30a | Affinity Capture-Western | 18598672 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ripk1 | Affinity Capture-Western | 19850933 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Prkcd | Affinity Capture-Western | 19850933 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Cyld | Affinity Capture-Western | 21878516 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Cul3 | Affinity Capture-Western | 22167182 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Atg16l1 | Affinity Capture-Western | 22167182 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Sqstm1 | Co-crystal Structure | 21715324 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Sod1 | Affinity Capture-Western | 19765191 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Sod1 | Co-localization | 19765191 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Map1lc3a | Affinity Capture-Western | 19765191 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Map1lc3a | Affinity Capture-Western | 18083104 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Sod1 | Affinity Capture-Western | 17296612 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Slc11a1 | Co-localization | 20206555 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Fau | Affinity Capture-Western | 20206555 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Map1lc3a | Reconstituted Complex | 18524774 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Keap1 | Reconstituted Complex | 20173742 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Keap1 | Affinity Capture-Western | 20173742 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Mapk1 | Reconstituted Complex | 16517408 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Mapk3 | Affinity Capture-Western | 20154642 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ulk1 | Affinity Capture-Western | 17389358 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Traf6 | Affinity Capture-Western | 17389358 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ar | Affinity Capture-Western | 23637164 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Map1lc3a | Affinity Capture-Western | 23637164 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ubc | Affinity Capture-Western | 23637164 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Trim55 | Affinity Capture-Western | 24124537 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ubc | Co-crystal Structure | 21715324 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Peli3 | Affinity Capture-Western | 25483963 | 10090 | 10090 | BIOGRID |
| Sqstm1 | CEP63 | Affinity Capture-Western | 27869116 | 10090 | 9606 | BIOGRID |
| Sqstm1 | CEP63 | Reconstituted Complex | 27869116 | 10090 | 9606 | BIOGRID |
| Sqstm1 | CEP63 | Co-localization | 27869116 | 10090 | 9606 | BIOGRID |
| Sqstm1 | Map1lc3b | FRET | 27442348 | 10090 | 10116 | BIOGRID |
| Sqstm1 | Sqstm1 | FRET | 27442348 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Keap1 | Affinity Capture-MS | 28820283 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Immt | Affinity Capture-MS | 28820283 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Samm50 | Affinity Capture-MS | 28820283 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Gnb4 | Affinity Capture-MS | 28820283 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Tax1bp1 | Affinity Capture-MS | 28820283 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Prkcz | Affinity Capture-Western | 26773517 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Lactb | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Gbas | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Letmd1 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Rps14 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Slc25a3 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Pycr2 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Suclg2 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Suclg1 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Tmem160 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Tecr | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Fut8 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ssr4 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ssb | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Elavl1 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Ruvbl1 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Rps3a1 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Psmc5 | Affinity Capture-MS | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Gbas | Affinity Capture-Western | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Tmem160 | Affinity Capture-Western | 30498063 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Tsg101 | Affinity Capture-Western | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Snai1 | Affinity Capture-MS | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Snai2 | Affinity Capture-MS | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Fn1 | Affinity Capture-MS | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Vim | Affinity Capture-MS | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Mmp2 | Affinity Capture-MS | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Mmp9 | Affinity Capture-MS | 31286822 | 10090 | 10090 | BIOGRID |
| Sqstm1 | UBC | Reconstituted Complex | 31362587 | 10090 | 9606 | BIOGRID |
| Sqstm1 | Ubc | Affinity Capture-Western | 31362587 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Keap1 | Affinity Capture-Western | 31362587 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Map1lc3a | Affinity Capture-Western | 32093570 | 10090 | 10090 | BIOGRID |
| Sqstm1 | Map1lc3a | Co-localization | 32093570 | 10090 | 10090 | BIOGRID |
Annotation of Sqstm1
Expression of Sqstm1
Disease information of Sqstm1